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L-精氨酸盐酸盐

氮供体合成一氧化氮
8篇引用文献 COA COA
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
A103485-100g
 100g 现货 Stock Image
A103485-500g
 500g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
查看相关系列
Amino acids (56) Immunology/Inflammation (1938) NO Synthase (134) 代谢物 (8911)
main product photo

基本描述

别名 盐酸精氨酸 | (S)-2-氨基-5-胍基戊酸盐酸盐 | L-(+)-精氨酸盐酸盐 | (S)-(+)-2-氨基-5-[(氨基亚甲基)氨基]戊酸 单盐酸盐 | (S)-(+)-精氨酸 盐酸盐
英文别名 (S)-2-Amino-5-guanidinopentanoic acid hydrochloride | L-ARGININE HCL | L-Arginine monohydrochloride, BioUltra, >=99.5% (AT) | NSC-203450 | ARGININE HYDROCHLORIDE [ORANGE BOOK] | ARGININE HYDROCHLORIDE [USAN] | L-ARGININE HYDROCHLORIDE [JAN] | H-Arg-OH.HCl
规格或纯度 PharmPure™, USP, JP, 欧洲药典（Ph.Eur）, 用于细胞培养, ≥98.5%
英文名称 L-Arginine hydrochloride
生化机理 一氧化氮合成酶的底物，可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。一氧化氮合酶（NOS）的底物，该酶转化为瓜氨酸和一氧化氮（NO）。通过一氧化氮依赖性机制诱导胰岛素释放。
应用 一氧化氮合成酶底物，能转换为瓜氨酸和NO。靠一种依赖于NO的机制诱导胰岛素分泌。
储存温度 充氩,干燥
运输条件 常规运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

无气味。溶于水，微溶于热乙醇，不溶于乙醚。水溶液呈酸性。218℃时熔结，225℃时成固态。一氧化氮合成酶底物，能转换为瓜氨酸和NO。靠一种依赖于NO的机制诱导胰岛素分泌。
纯度 ≥98.5%

关联靶点（人）

F2 Tclin Thrombin (11687 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 214-275-1
分子类型 小分子
IIUPAC Name (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
INCHI 1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChi Key KWTQSFXGGICVPE-WCCKRBBISA-N
Smiles Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
Isomeric SMILES C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
关联CAS 15595-35-4
分子量 210.66
Beilstein号 6099937
Reaxy-Rn 3631658
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3631658&ln=

化学和物理性质

溶解性 Soluble in water. Slightly soluble in hot alcohol.
密度 1.46
敏感性 对光及湿度敏感
比旋光度 23 ° (C=8, HCl(1+1))
熔点 226-230°C
分子量 210.660 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 5
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 5
精确质量Exact Mass 210.088 Da
单同位素质量Monoisotopic Mass 210.088 Da
拓扑极表面积Topological Polar Surface Area 128.000 Ų
重原子数Heavy Atom Count 13
形式电荷Formal Charge 0
复杂度Complexity 176.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 2

安全和危险性（GHS）

象形图 GHS07
信号词 警告
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激
预防措施声明

P264: 处理后要彻底洗手。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany 1
Merck Index 780
个人防护装备 Eyeshields,Gloves

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批号(Lot Number) 证书类型 货号
H2528126 分析证书 A103485
F2512112 分析证书 A103485
F2512132 分析证书 A103485
C2511058 分析证书 A103485
C2521874 分析证书 A103485
K2413159 分析证书 A103485
I2429083 分析证书 A103485
H2415076 分析证书 A103485
E2428031 分析证书 A103485
E2428029 分析证书 A103485
E2428030 分析证书 A103485
L2311150 分析证书 A103485
D23061236 分析证书 A103485
K2204216 分析证书 A103485
K2204217 分析证书 A103485
B2301186 分析证书 A103485
G1429035 分析证书 A103485

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引用文献

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