2,2'-二氨基二苯二硫醚

21篇引用文献

COA

级别和纯度:

≥98%

CAS编号: 1141-88-4
分子式: (H₂NC₆H₄)₂S₂
分子量: 248.37
Beilstein号: 914032
EC号: 214-529-1
MDL号: MFCD00007703
PubChem编号: 14358
PubChem SID: 488181987

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货号 (SKU)	包装规格	是否现货
A101816-1g	1g	现货
A101816-5g	5g	现货
A101816-25g	25g	现货
A101816-100g	100g	现货
A101816-500g	500g	现货

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二胺单体 (21) 聚合物/高分子试剂 (683)

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基本描述

别名	二(邻氨基)苯基二硫 \| 双(2-氨基苯基)二硫 \| 2,2'-二氨基二苯基二硫 \| 2,2'-二硫代二苯胺
英文别名	2,2'-Diaminodiphenyldisulfide \| bis-(2-aminophenyl)disulfide \| Bis(2-aminophenyl)disulfide \| Bis(o-aminophenyl) disulfide \| cid_14358 \| NSC 677450 \| AMY22526 \| 2-[(2-Aminophenyl)disulfanyl]phenylamine \| Di(2-aminophenyl) Disulfide \| D72491 \| Disulfide, bi
规格或纯度	≥98%
英文名称	2-Aminophenyl disulfide
运输条件	常规运输
产品介绍	2,2'-Diaminodiphenyl disulfide, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used as a primary and secondary intermediate.
纯度	≥98%

关联靶点（人）

VDR Tclin Vitamin D receptor (26531 活性数据)

点击查看靶蛋白信息： VDR

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 活性数据)

点击查看靶蛋白信息： PLK1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 活性数据)

点击查看靶蛋白信息： GLP1R

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 活性数据)

点击查看靶蛋白信息： TP53

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

FEN1 Tchem Flap endonuclease 1 (12055 活性数据)

点击查看靶蛋白信息： FEN1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

POLI Tchem DNA polymerase iota (116820 活性数据)

点击查看靶蛋白信息： POLI

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

KDM4A Tchem Lysine-specific demethylase 4A (52245 活性数据)

点击查看靶蛋白信息： KDM4A

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)

点击查看靶蛋白信息： APEX1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)

点击查看靶蛋白信息： EHMT2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)

点击查看靶蛋白信息： TDP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 活性数据)

点击查看靶蛋白信息： SMAD3

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)

点击查看靶蛋白信息： CBX1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 活性数据)

点击查看靶蛋白信息： ATAD5

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

APOBEC3G Tchem DNA dC->dU-editing enzyme APOBEC-3G (12481 活性数据)

点击查看靶蛋白信息： APOBEC3G

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 活性数据)

点击查看靶蛋白信息： BAZ2B

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ATXN2 Tbio Ataxin-2 (54410 活性数据)

点击查看靶蛋白信息： ATXN2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 活性数据)

点击查看靶蛋白信息： USP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RGS4 Tchem Regulator of G-protein signaling 4 (13867 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RACGAP1 Tbio Rac GTPase-activating protein 1 (2057 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Saccharomyces cerevisiae (19171 活性数据)

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Plasmodium falciparum (966862 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Human immunodeficiency virus 1 (70413 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Npsr1 Neuropeptide S receptor (260 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

pfk 6-phospho-1-fructokinase (7870 活性数据)

点击查看靶蛋白信息： pfk

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 活性数据)

点击查看靶蛋白信息： Txnrd1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ddn Putative uncharacterized protein (49 活性数据)

点击查看靶蛋白信息： ddn

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 活性数据)

点击查看靶蛋白信息： Mapt

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 活性数据)

点击查看靶蛋白信息： Rorc

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)

点击查看靶蛋白信息： fba

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)

点击查看靶蛋白信息： ffp

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 活性数据)

点击查看靶蛋白信息： FTL

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NS1 Nonstructural protein 1 (33327 活性数据)

点击查看靶蛋白信息： NS1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488181987
EC号	214-529-1
分子类型	小分子
IIUPAC Name	2-[(2-aminophenyl)disulfanyl]aniline
INCHI	1S/C12H12N2S2/c13-9-5-1-3-7-11(9)15-16-12-8-4-2-6-10(12)14/h1-8H,13-14H2
InChi Key	YYYOQURZQWIILK-UHFFFAOYSA-N
Smiles	C1=CC=C(C(=C1)N)SSC2=CC=CC=C2N
Isomeric SMILES	C1=CC=C(C(=C1)N)SSC2=CC=CC=C2N
分子量	248.37
Beilstein号	914032
Reaxy-Rn	914032
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=914032&ln=

化学和物理性质

溶解性	Insoluble in water, soluble in methanol, ethanol
密度	1.1039
熔点	91-92°C
分子量	248.400 g/mol
XLogP3	3.100
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	248.044 Da
单同位素质量Monoisotopic Mass	248.044 Da
拓扑极表面积Topological Polar Surface Area	103.000 Å²
重原子数Heavy Atom Count	16
形式电荷Formal Charge	0
复杂度Complexity	191.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS05, GHS06, GHS07, GHS09
信号词	危险
危险声明	H301: 吞咽会中毒 H302: 吞食有害 H315: 引起皮肤刺激 H317: 可能引起皮肤过敏反应 H318: 造成严重的眼睛损伤 H400: 对水生生物有剧毒 H410: 对水生生物有剧毒并具有长期持续影响 H411: 对水生生物有毒并具有长期持续影响
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P272: 被污染的工作服不允许离开工作场所 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P391: 收集溢出物 P302+P352: 如皮肤沾染：用水充分清洗。 P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany	2
RTECS	BX9540000
个人防护装备	dust mask type N95 (US),Eyeshields,Gloves

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批号(Lot Number)	证书类型	货号
I2506024	分析证书	A101816
D2525090	分析证书	A101816
D2525091	分析证书	A101816
D2525092	分析证书	A101816
D2525093	分析证书	A101816
B2507035	分析证书	A101816
L2411769	分析证书	A101816
L2411777	分析证书	A101816
L2411778	分析证书	A101816
L2411779	分析证书	A101816
J2428579	分析证书	A101816
J2428588	分析证书	A101816
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J2428581	分析证书	A101816
G2418443	分析证书	A101816
G2418444	分析证书	A101816
G2418445	分析证书	A101816
G2418428	分析证书	A101816
G2418442	分析证书	A101816
G2404130	分析证书	A101816
D2403685	分析证书	A101816
F2002061	分析证书	A101816
A2405065	分析证书	A101816
G2230012	分析证书	A101816
G2230014	分析证书	A101816
G2230015	分析证书	A101816
G2230016	分析证书	A101816
B2310272	分析证书	A101816
B2322279	分析证书	A101816
B2322280	分析证书	A101816
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引用文献

1. T Benjamin, R P Evarts, T V Reddy, E K Weisburger,. (1981-01-01) Effect of 2,2'-diaminodiphenyldisulfide, a resin hardener, on rats.. Journal of toxicology and environmental health, 7 ((1)): ( 69-81 ). [PMID:7265299]
2. Haibin Niu, Jiaqi Li, Xin Song, Kaiyang Zhao, Li Liu, Chao Zhou, Guangfeng Wu. (2024) Multifunctional aqueous polyurethanes with high strength and self-healing efficiency based on silver nanowires for flexible strain sensors. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 26 (3): (2175-2189). [PMID:38164717] [10.1039/D3CP04319C]
3. Tao Cheng, Wangwei Lian, Weizhen Zhang, Jie Wang, Chenchen Wu, Bo Lu, Kunlun Tan, Binbin Dong, Chuntai Liu, Changyu Shen. (2023) Room-Temperature Self-Repairable Yet Mechanically Robust Elastomeric Triboelectric Nanogenerators Enabled by a Fast-Reversible Dual-Dynamic Network. ACS Sustainable Chemistry & Engineering, 11 (39): (14376–14390). [10.1021/acssuschemeng.3c02399]
4. Wangjian Cheng, Dongjie Liao, Chenhe Feng, Fubing Gao, Minjie Li, Xiawei Zhang, Lingyu Deng, Chuanhao Xu, Baoyun Ye, Chongwei An. (2023) Development of robust and rapid self-healing polymers for the repair of microcracks in energetic composite materials. EUROPEAN POLYMER JOURNAL, 197 (112375). [10.1016/j.eurpolymj.2023.112375]
5. Geonwoo Kim, Cigdem Caglayan, Gun Jin Yun. (2022) Epoxy-Based Catalyst-Free Self-Healing Elastomers at Room Temperature Employing Aromatic Disulfide and Hydrogen Bonds. ACS Omega, 7 (49): (44750–44761). [PMID:36530289] [10.1021/acsomega.2c04559]
6. Yujia Hao, Guangming Zhu, Ben Li, Tianning Ren. (2022) A high-performance self-healing polyurea material based on exchangeable aromatic disulfide. JOURNAL OF APPLIED POLYMER SCIENCE, 139 (41): (e52992). [10.1002/app.52992]
7. Yuanhao Ma, Rui Qin, Min Xu, Xiaolin Jiang, Yeming Sheng, Minhui Wang, Wencong Zhang, Xun Lu. (2021) Wide temperature range damping polyurethane elastomer based on dynamic disulfide bonds. JOURNAL OF APPLIED POLYMER SCIENCE, 139 (2): (51453). [10.1002/app.51453]
8. Yahao Liu, Jian Zheng, Xiao Zhang, Yongqiang Du, Guibo Yu, Ke Li, Yunfei Jia, Yu Zhang. (2021) Bioinspired modified graphene oxide/polyurethane composites with rapid self-healing performance and excellent mechanical properties. RSC Advances, 11 (24): (14665-14677). [PMID:35423966] [10.1039/D1RA00944C]
9. Yahao Liu, Jian Zheng, Xiao Zhang, Yongqiang Du, Ke Li, Guibo Yu, Yunfei Jia, Yu Zhang. (2021) Mussel-inspired and aromatic disulfide-mediated polyurea-urethane with rapid self-healing performance and water-resistance. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 593 (105). [PMID:33744521] [10.1016/j.jcis.2021.03.003]
10. Huihua Huang, Wei Zhou, Ziyuan Zhong, Shuangshuang Peng, Xiaohong Peng. (2020) Self-antiglare waterborne coating with superior mechanical robustness and highly efficient room-temperature self-healing capability. PROGRESS IN ORGANIC COATINGS, 146 (105717). [10.1016/j.porgcoat.2020.105717]
11. Li Zi-Jian, Zhong Jiang, Liu Mao-Chen, Rong Jin-Chuang, Yang Kun, Zhou Ji-Yong, Shen Liang, Gao Fei, He Hai-Feng. (2020) Investigation on Self-healing Property of Epoxy Resins Based on Disulfide Dynamic Links. CHINESE JOURNAL OF POLYMER SCIENCE, 38 (9): (932-940). [10.1007/s10118-020-2406-x]
12. Zheng Yue Wang, Yang You, Min Zhi Rong, Ming Qiu Zhang. (2024) A Facile Strategy to Bond Chemically Different Materials Based on Interfacial Interlocked Polymer Networks. ACS Applied Polymer Materials, 7 (1): (73-82). [10.1021/acsapm.4c02657]
13. Yan Li, Haibo Feng, Jing Xiong, Li Li. (2024) A Group-Enriched Viscoelastic Model for High-Damping Vitrimers with Many Dangling Chains. Materials, 17 (20): (5062). [PMID:39459767] [10.3390/ma17205062]
14. Zheng Qiaoyang, Jiang Xiaolin, Lu Xun. (2024) A multi-functional polyurethane elastomer with high damping, water resistance and flame retardancy. REACTIVE & FUNCTIONAL POLYMERS, 196 (105838). [10.1016/j.reactfunctpolym.2024.105838]
15. Jiaqi Li, Fengqing Zhang, Haibin Nu, Chao Zhou, Guangfeng Wu. (2025) Asymmetric, continuum-structured self-healable composite conductors based on WPU/MXene/AgNW with microphase-separated structures for balanced healing and mechanical properties. MICROCHEMICAL JOURNAL, 208 (112529). [10.1016/j.microc.2024.112529]
16. Mianji Qiu, Zhi Geng, Wangjian Cheng, Chengyuan Hua, Xing Yan, Baoyun Ye, Chongwei An, Jingyu Wang. (2025) Construction of a novel GAP/PCL energetic self-healing blend adhesive system for propellants based on the synergistic effect of hydrogen bond reorganization and disulfide bond exchange reactions. EUROPEAN POLYMER JOURNAL, 229 (113860). [10.1016/j.eurpolymj.2025.113860]
17. Long Yi, Shijie Song, Ying Liu. (2025) Fabrication of functionalized boron nitride modified self-healing composite coating for corrosion and wear protection. COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING, 191 (108747). [10.1016/j.compositesa.2025.108747]
18. Geonwoo Kim, Cigdem Caglayan, Gun Jin Yun. (2024) High Modulus Epoxy/GO-PANI Self-Healing Materials Without Catalyst by Molecular Engineering and Nanocomposite Fabrication. Polymers, 16 (22): (3173). [PMID:39599264] [10.3390/polym16223173]
19. Haibin Niu, Li Liu, Yanmei Zhu, Chao Zhou, Guangfeng Wu. (2024) Liquid metal-enhanced self-healing dual-hard-phase cross-linked waterborne polyurethane for flexible sensors. EUROPEAN POLYMER JOURNAL, 215 (113185). [10.1016/j.eurpolymj.2024.113185]
20. Jiaofeng Ye, Junxiang Zhang, Libang Feng, Haocheng Liu, Danbin Zhu, Yanhua Liu. (2024) Polyurethane combining preeminent toughness, puncture-resistance, and self-healing capabilities by multiple repair options based on dual dynamic covalent bonds. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 694 (134203). [10.1016/j.colsurfa.2024.134203]
21. Hechen Liu, Chang Liu, Yunpeng Liu, Yuzhe Jiang, Xinyang Li, Yining Bai. (2024) Rapid repair and degradation: A study of high-performance recyclable vitrimer epoxy resin based on disulfide bonds. POLYMER TESTING, 137 (108528). [10.1016/j.polymertesting.2024.108528]
22. Yang Han, Xude Qin, Qianqian Kang, Weijie Fan, Dongxiao Han, Yantong Pei, Ye Chen, Wei Wang. (2024) Self-Healing TiO2/Ti3C2Tx/PDMS Coating with High Mechanical Robustness and Anticorrosion Performance. ACS Applied Polymer Materials, 6 (15): (9069-9079). [10.1021/acsapm.4c01360]

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g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度