基本描述

别名	1-氨基环己甲酸 \| 1-氨基环己烷羧酸 \| 1-氨基环己烷甲酸
英文别名	1-Aminocyclohexane-1-carboxylic acid \| AC1NOMHH \| Lopac-A-162 \| NCGC00015011-01 \| EN300-17792 \| HMS1789H14 \| 2-aminocyclohexane-2-carboxylic acid \| ZINC00116197 \| 1-Aminocyclohexanecarboxylic acid \| 1-amino-cyclohexanecarboxylic acid \| SY002600 \| 1-Amino-
规格或纯度	≥98%
英文名称	1-Aminocyclohexanecarboxylic acid
储存温度	干燥
运输条件	常规运输
纯度	≥98%

关联靶点（人）

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)

点击查看靶蛋白信息： CHRM1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ARSA Tbio Cerebroside-sulfatase (655 活性数据)

点击查看靶蛋白信息： ARSA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)

点击查看靶蛋白信息： CYP2D6

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)

点击查看靶蛋白信息： CYP1A2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)

点击查看靶蛋白信息： CYP2C9

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)

点击查看靶蛋白信息： CYP2C19

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)

点击查看靶蛋白信息： EHMT2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)

点击查看靶蛋白信息： CBX1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Grin1 Glutamate NMDA receptor (6467 活性数据)

点击查看靶蛋白信息： Grin1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504750484
EC号	220-411-0
分子类型	小分子
IIUPAC Name	1-aminocyclohexane-1-carboxylic acid
INCHI	1S/C7H13NO2/c8-7(6(9)10)4-2-1-3-5-7/h1-5,8H2,(H,9,10)
InChi Key	WOXWUZCRWJWTRT-UHFFFAOYSA-N
Smiles	C1CCC(CC1)(C(=O)O)N
Isomeric SMILES	C1CCC(CC1)(C(=O)O)N
分子量	143.18
Beilstein号	2355692
Reaxy-Rn	2355692
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2355692&ln=

化学和物理性质

溶解性	Solubility in Water almost transparency
密度	1.148
敏感性	易吸潮
熔点	＞300°C
分子量	143.180 g/mol
XLogP3	-1.900
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	1
精确质量Exact Mass	143.095 Da
单同位素质量Monoisotopic Mass	143.095 Da
拓扑极表面积Topological Polar Surface Area	63.300 Å²
重原子数Heavy Atom Count	10
形式电荷Formal Charge	0
复杂度Complexity	139.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS05, GHS07
信号词	危险
危险声明	H315: 引起皮肤刺激 H318: 造成严重的眼睛损伤
预防措施声明	P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany	3
RTECS	GU8393000
个人防护装备	Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到8个结果

批号(Lot Number)	证书类型	货号
A2206607	分析证书	A101237
A2206633	分析证书	A101237
I2116026	分析证书	A101237
I2116027	分析证书	A101237
I2116028	分析证书	A101237
J1921001	分析证书	A101237
H2310062	分析证书	A101237
H2310066	分析证书	A101237

引用文献

1. M Aoyagi,B W Agranoff,L C Washburn,Q R Smith. (1988-04-01) Blood-brain barrier transport of 1-aminocyclohexanecarboxylic acid, a nonmetabolizable amino acid for in vivo studies of brain transport.. Journal of neurochemistry, 50 ((4)): (1220-1226). [PMID:3346675]
2. M Sukumar,P A Raj,P Balaram,E L Becker. (1985-04-16) A highly active chemotactic peptide analog incorporating the unusual residue 1-aminocyclohexanecarboxylic acid at position 2.. Biochemical and biophysical research communications, 128 ((1)): (339-344). [PMID:3985973]
3. B L Shulkin,A L Betz,R A Koeppe,B W Agranoff. (1995-03-01) Inhibition of neutral amino acid transport across the human blood-brain barrier by phenylalanine.. Journal of neurochemistry, 64 ((3)): (1252-1257). [PMID:7861158]
4. A Romanelli,I Garella,V Menchise,R Iacovino,M Saviano,D Montesarchio,C Didierjean,P Di Lello,F Rossi,E Benedetti. (2001-03-14) Crystal-state conformation of Calpha,alpha-dialkylated peptides containing chiral beta-homo-residues.. Journal of peptide science : an official publication of the European Peptide Society, 7 ((1)): (15-26). [PMID:11245201]
5. Fernando Formaggio,Marcella Bonchio,Marco Crisma,Cristina Peggion,Stefano Mezzato,Alessandra Polese,Alessandra Barazza,Sabrina Antonello,Flavio Maran,Quirinus B Broxterman,Bernard Kaptein,Johan Kamphuis,Rosa Maria Vitale,Michele Saviano,Ettore Benedetti,Claudio Toniolo. (2002-02-02) Nitroxyl peptides as catalysts of enantioselective oxidations.. Chemistry (Weinheim an der Bergstrasse, Germany), 8 ((1)): (84-93). [PMID:11822466]
6. B Jastrzebska,I Derdowska,W Kowalczyk,A Machova,J Slaninová,B Lammek. (2003-06-26) Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties.. The journal of peptide research : official journal of the American Peptide Society, 62 ((2)): (70-77). [PMID:12823619]
7. Olga Labudda-Dawidowska,Tomasz H Wierzba,Adam Prahl,Wioleta Kowalczyk,Łukasz Gawiński,Marketa Plackova,Jirina Slaninová,Bernard Lammek. (2005-12-13) New bradykinin analogues modified in the C-terminal part with sterically restricted 1-aminocyclohexane-1-carboxylic acid.. Journal of medicinal chemistry, 48 ((25)): (8055-8059). [PMID:16335929]
8. Olga Labudda,Tomasz Wierzba,Dariusz Sobolewski,Wioleta Kowalczyk,Małgorzata Sleszyńska,Lukasz Gawiński,Marketa Plackova,Jirina Slaninová,Adam Prahl. (2006-11-30) New bradykinin analogues substituted in positions 7 and 8 with sterically restricted 1-aminocyclopentane-1-carboxylic acid.. Journal of peptide science : an official publication of the European Peptide Society, 12 ((12)): (775-779). [PMID:17131289]
9. Francisco Rodríguez-Ropero,David Zanuy,Jordi Casanovas,Ruth Nussinov,Carlos Alemán. (2008-01-19) Application of 1-aminocyclohexane carboxylic acid to protein nanostructure computer design.. Journal of chemical information and modeling, 48 ((2)): (333-343). [PMID:18201062]
10. Stephan Urwyler,Philipp Floersheim,Bernard L Roy,Manuel Koller. (2009-08-01) Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex.. Journal of medicinal chemistry, 52 ((16)): (5093-5107). [PMID:19642674]
11. B M Tashtoush,A A Traboulsi,L Dittert,A A Hussain. (2001-01-06) Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques.. Analytical biochemistry, 288 ((1)): (16-21). [PMID:11141301]
12. Mitsunobu Doi,Akiko Asano,Eri Komura,Yoko Ueda. (2002-09-11) The structure of an endomorphin analogue incorporating 1-aminocyclohexane-1-carboxlylic acid for proline is similar to the beta-turn of Leu-enkephalin.. Biochemical and biophysical research communications, 297 ((1)): (138-142). [PMID:12220521]
13. Wioleta Kowalczyk,Adam Prahl,Izabela Derdowska,Olga Dawidowska,Jirina Slaninová,Bernard Lammek. (2004-11-13) Highly potent 1-aminocyclohexane-1-carboxylic acid substituted V2 agonists of arginine vasopressin.. Journal of medicinal chemistry, 47 ((24)): (6020-6024). [PMID:15537356]
14. Edyta Podstawka,Emilia Sikorska,Leonard M Proniewicz,Bernard Lammek. (2006-06-03) Raman and surface-enhanced Raman spectroscopy investigation of vasopressin analogues containing 1-aminocyclohexane-1-carboxylic acid residue.. Biopolymers, 83 ((2)): (193-203). [PMID:16741975]
15. Nicolas Fabresse,Fanta Fall,Isabelle Etting,Philippe Devillier,Jean-Claude Alvarez,Stanislas Grassin-Delyle. (2017-04-27) LC-MS/MS determination of tranexamic acid in human plasma after phospholipid clean-up.. Journal of pharmaceutical and biomedical analysis, 141 (149-156). [PMID:28445815]
16. Raquel Pérez-Míguez,María Castro-Puyana,Elena Sánchez-López,Merichel Plaza,María Luisa Marina. (2020-02-23) Untargeted HILIC-MS-Based Metabolomics Approach to Evaluate Coffee Roasting Process: Contributing to an Integrated Metabolomics Multiplatform.. Molecules (Basel, Switzerland), 25 ((4)): [PMID:32079306]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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浓度

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体积

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分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

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体积 1 (V1)

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浓度 2 (C2)

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体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

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质量（小瓶）

÷

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
A101237-5g	5g	现货
A101237-25g	25g	现货
A101237-100g	100g	现货

1-氨基-1-环己基甲酸

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器