基本描述

别名	乙酰-L-亮氨酸 \| N-乙酰-L-白氨酸 \| N-乙酰基-L-亮氨酸
英文别名	KBioSS_001793 \| N-Acetyl-L-leucine, ReagentPlus(R), 99% \| DivK1c_001317 \| KBio2_001793 \| Ac-Leu-OH \| Carbazochrom \| N-ACETYL-L-(-)-LEUCINE \| AB00052251_03 \| KBioGR_000471 \| AKOS010400978 \| Bornan-2-one \| HMS2097D14 \| N-Acetyl-L-leucine, Vetec(TM) reagent
规格或纯度	≥99%
英文名称	N-Acetyl-L-leucine
运输条件	常规运输
纯度	≥99%

关联靶点（人）

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)

点击查看靶蛋白信息： ALDH1A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)

点击查看靶蛋白信息： CYP2D6

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)

点击查看靶蛋白信息： CYP1A2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)

点击查看靶蛋白信息： CYP2C9

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)

点击查看靶蛋白信息： CYP2C19

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 活性数据)

点击查看靶蛋白信息： SLCO1B1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 活性数据)

点击查看靶蛋白信息： SLCO1B3

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Hdac6 Histone deacetylase 6 (222 活性数据)

点击查看靶蛋白信息： Hdac6

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 活性数据)

点击查看靶蛋白信息： rep

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488184616
EC号	214-706-3
分子类型	小分子
IIUPAC Name	(2S)-2-acetamido-4-methylpentanoic acid
INCHI	1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1
InChi Key	WXNXCEHXYPACJF-ZETCQYMHSA-N
Smiles	CC(C)CC(C(=O)O)NC(=O)C
Isomeric SMILES	CC(C)C[C@@H](C(=O)O)NC(=O)C
分子量	173.21
Beilstein号	1724849
Reaxy-Rn	1724848
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1724848&ln=

化学和物理性质

溶解性	Soluble in water (partly), ethanol (5%), and methanol.
密度	1.069
折光率	1.46
比旋光度	-24o±2o, c = 4 in methanol
沸点	369.6 °C
熔点	190°C
分子量	173.210 g/mol
XLogP3	0.500
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	4
精确质量Exact Mass	173.105 Da
单同位素质量Monoisotopic Mass	173.105 Da
拓扑极表面积Topological Polar Surface Area	66.400 Å²
重原子数Heavy Atom Count	12
形式电荷Formal Charge	0
复杂度Complexity	177.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
WGK Germany	3

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到10个结果

批号(Lot Number)	证书类型	货号
G2114062	分析证书	A101039
G2114063	分析证书	A101039
J1618002	分析证书	A101039
B2321053	分析证书	A101039
H2209036	分析证书	A101039
H2209037	分析证书	A101039
H2209038	分析证书	A101039
H2209040	分析证书	A101039
B2321047	分析证书	A101039
B2321048	分析证书	A101039

此产品的引用文献

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引用文献

1. A Ramamoorthy,C H Wu,S J Opella. (1995-04-01) Three-dimensional solid-state NMR experiment that correlates the chemical shift and dipolar coupling frequencies of two heteronuclei.. Journal of magnetic resonance. Series B, 107 ((1)): (88-90). [PMID:7743077]
2. R Hirschmann,A B Smith,C M Taylor,P A Benkovic,S D Taylor,K M Yager,P A Sprengeler,S J Benkovic. (1994-07-08) Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.. Science (New York, N.Y.), 265 ((5169)): (234-237). [PMID:8023141]
3. T Suzuki,T Ueda,K Watanabe. (1996-03-04) A new method for identifying the amino acid attached to a particular RNA in the cell.. FEBS letters, 381 ((3)): (195-198). [PMID:8601454]
4. A Pertsemlidis,A M Saxena,A K Soper,T Head-Gordon,R M Glaeser. (1996-10-01) Direct evidence for modified solvent structure within the hydration shell of a hydrophobic amino acid.. Proceedings of the National Academy of Sciences of the United States of America, 93 ((20)): (10769-10774). [PMID:8855255]
5. J Sun. (1997-08-01) [Effects of acetyl-DL-leucine on the recovery of the locomotor equilibrium and spontaneous discharge of lateral vestibular nucleus neurons in unilateral vestibular neurectomized cats].. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 13 ((3)): (257-260). [PMID:10074280]
6. A Ramamoorthy,C H Wu,S J Opella. (1999-09-10) Experimental aspects of multidimensional solid-state NMR correlation spectroscopy.. Journal of magnetic resonance (San Diego, Calif. : 1997), 140 ((1)): (131-140). [PMID:10479555]
7. N Vibert,P P Vidal. (2001-02-24) In vitro effects of acetyl-DL-leucine (tanganil) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig.. The European journal of neuroscience, 13 ((4)): (735-748). [PMID:11207808]
8. D H Jones,S J Opella. (2005-12-14) Application of Maximum Entropy reconstruction to PISEMA spectra.. Journal of magnetic resonance (San Diego, Calif. : 1997), 179 ((1)): (105-113). [PMID:16343957]
9. Chin H Wu,Stanley J Opella. (2008-02-13) Shiftless nuclear magnetic resonance spectroscopy.. The Journal of chemical physics, 128 ((5)): (052312-052312). [PMID:18266429]
10. T Gopinath,Nathaniel J Traaseth,Kaustubh Mote,Gianluigi Veglia. (2010-03-30) Sensitivity enhanced heteronuclear correlation spectroscopy in multidimensional solid-state NMR of oriented systems via chemical shift coherences.. Journal of the American Chemical Society, 132 ((15)): (5357-5363). [PMID:20345172]
11. Yukako Komaki,Adam M-A Simpson,Jong Kwon Choe,Margaux M Pinney,Daniel Herschlag,Yi-Hsueh Chuang,William A Mitch. (2019-07-28) Serum electrolytes can promote hydroxyl radical-initiated biomolecular damage from inflammation.. Free radical biology & medicine, 141 (475-482). [PMID:31349038]
12. Grant C Churchill,Michael Strupp,Antony Galione,Frances M Platt. (2020-02-29) Unexpected differences in the pharmacokinetics of N-acetyl-DL-leucine enantiomers after oral dosing and their clinical relevance.. PloS one, 15 ((2)): (e0229585-e0229585). [PMID:32108176]
13. P Benard,H Cousse,T Bengone,C Germain. (2001-09-14) Autoradiography in brain of Macaca fascicularis monkeys after injection of acetyl-DL-leucine [2-14C] (Tanganil).. European journal of drug metabolism and pharmacokinetics, 26 ((1-2)): (71-76). [PMID:11554437]
14. Zhaoxiong Zheng,Wei Qiang,David P Weliky. (2007-12-25) Investigation of finite-pulse radiofrequency-driven recoupling methods for measurement of intercarbonyl distances in polycrystalline and membrane-associated HIV fusion peptide samples.. Magnetic resonance in chemistry : MRC, 45 Suppl 1 (S247-S260). [PMID:18157840]
15. Gilles Clément,Olivier Deguine,Mathieu Bourg,Anne Pavy-LeTraon. (2008-07-16) Effects of vestibular training on motion sickness, nystagmus, and subjective vertical.. Journal of vestibular research : equilibrium & orientation, 17 ((5-6)): (227-237). [PMID:18626134]
16. C Ferber-Viart,C Dubreuil,P P Vidal. (2008-07-30) Effects of acetyl-DL-leucine in vestibular patients: a clinical study following neurotomy and labyrinthectomy.. Audiology & neuro-otology, 14 ((1)): (17-25). [PMID:18663295]
17. T Gopinath,Gianluigi Veglia. (2009-04-09) Sensitivity enhancement in static solid-state NMR experiments via single- and multiple-quantum dipolar coherences.. Journal of the American Chemical Society, 131 ((16)): (5754-5756). [PMID:19351170]
18. Nathaniel J Traaseth,T Gopinath,Gianluigi Veglia. (2010-10-13) On the performance of spin diffusion NMR techniques in oriented solids: prospects for resonance assignments and distance measurements from separated local field experiments.. The journal of physical chemistry. B, 114 ((43)): (13872-13880). [PMID:20936833]
19. Alexander A Nevzorov. (2011-02-08) Ergodicity and efficiency of cross-polarization in NMR of static solids.. Journal of magnetic resonance (San Diego, Calif. : 1997), 209 ((2)): (161-166). [PMID:21296016]
20. Yaoguo Wang, Jie Sun, Weiwei Tang, Junbo Gong. (2023) Green chiral separation of racemic mixture via crystallization induced deracemization process synergistically intensified by ultrasound and temperature cycling. CHEMICAL ENGINEERING SCIENCE, 281 (119115). [10.1016/j.ces.2023.119115]
21. Lu Hou, Zheyu Song, Zhonghang Xu, Yuanyu Wu, Wei Shi. (2020) Folate-Mediated Targeted Delivery of siPLK1 by Leucine-Bearing Polyethylenimine. International Journal of Nanomedicine, 15 ( 1397–1408). [PMID:32184594] [10.2147/IJN.S227289]
22. Shengzheng Guo, Yang He, Gang Wang, Weibing Dong, Xuxing Wan, Yanxiao Zhao, Shichao Du. (2020) Solubility Measurement, Correlation, and Thermodynamic Analysis of N-Acetyl-l-leucine in 12 Pure Organic Solvents from 283.15 to 323.15 K. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 65 (4): (2008–2016). [10.1021/acs.jced.9b01151]
23. Dandan Wang, Liangxiao Zhang, Yueqing Xu, Xin Qi, Xuefang Wang, Xiupin Wang, Qi Zhang, Peiwu Li. (2019) Optimization of an Ultrasound-Assisted Extraction for Simultaneous Determination of Antioxidants in Sesame with Response Surface Methodology. Antioxidants, 8 (8): (321). [PMID:31430991] [10.3390/antiox8080321]
24. Zhiyuan Li, Liu Zhang, Quanshun Li. (2015) Induction of apoptosis in cancer cells through N-acetyl-l-leucine-modified polyethylenimine-mediated p53 gene delivery. COLLOIDS AND SURFACES B-BIOINTERFACES, 135 (630). [PMID:26322477] [10.1016/j.colsurfb.2015.08.024]
25. Mingyuan Dou, Qing Feng, Jing Yang, Shuai Zou, Kangchun Li, Zhenpeng Li, Maoli Yang, Fuchuan Huang. (2024) Evaluation of rheological properties and tribological properties of choline/acetylamino acid ionic liquids at different frequencies. WEAR, 540-541 (205247). [10.1016/j.wear.2024.205247]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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浓度

x

体积

x

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

x

体积 1 (V1)

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浓度 2 (C2)

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体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

=

质量（小瓶）

÷

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
A101039-5g	5g	现货
A101039-25g	25g	现货
A101039-100g	100g	现货
A101039-500g	500g	现货

N-乙酰-L-亮氨酸

库存信息

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器