基本描述

别名	丙氨酸甲脂盐酸盐 \| (S)-2-氨基丙酸甲酯盐酸盐
英文别名	methyl (2S)-2-aminopropanoate hydrochloride \| (S)-Methyl 2-aminopropanoate hydrochloride \| Methyl L-alaninate hydrochloride \| (S)-2-Aminopropionic Acid Methyl Ester Hydrochloride \| H-Ala-OMe.HCl \| MFCD00063663 \| (L)-Alanine methyl ester hydrochloride \| L-
规格或纯度	≥98%
英文名称	L-Alanine methyl ester hydrochloride
储存温度	2-8°C储存,充氩
运输条件	冰袋运输
产品介绍	L-丙氨酸甲酯盐酸盐，又称为L-Ala-OMe·HCl，是一种多功能试剂，常用于液相多肽合成法。常用于合成二肽。应用： L-丙氨酸甲酯盐酸盐可作为起始材料用于液相多肽合成法合成丙氨酸异恶唑烷(alanine isoxazolidide)。也用于合成N-Fmoc-l-丙氨酰-l-丙氨酸甲酯和α-氨基酸基树枝化基元(sector block dendrons)。 L-Alanine methyl ester hydrochloride also known as L-Ala-OMe·HCl, is a versatile reagent used commonly in solution phase peptide synthesis. It is often used to synthesize dipeptides. Application L-Alanine methyl ester hydrochloride can be used as a starting material in the synthesis of alanine isoxazolidide via solution phase peptide synthesis. Additionally, it is used to synthesize N-Fmoc-l-alanyl-l-alanine methyl ester and α-amino acid-based sector block dendrons.
纯度	≥98%

关联靶点（其它种属）

GAP1 General amino-acid permease GAP1 (481 活性数据)

点击查看靶蛋白信息： GAP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504760977
EC号	219-652-4
分子类型	小分子
IIUPAC Name	methyl (2S)-2-aminopropanoate;hydrochloride
INCHI	1S/C4H9NO2.ClH/c1-3(5)4(6)7-2;/h3H,5H2,1-2H3;1H/t3-;/m0./s1
InChi Key	IYUKFAFDFHZKPI-DFWYDOINSA-N
Smiles	Cl.COC(=O)[C@H](C)N
Isomeric SMILES	C[C@@H](C(=O)OC)N.Cl
分子量	139.58
Beilstein号	3594033
Reaxy-Rn	3594033
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3594033&ln=

化学和物理性质

敏感性	对湿度敏感
比旋光度	6.5 ° (C=2, MeOH)
熔点	109-111°C
分子量	139.580 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	3
可旋转键计数Rotatable Bond Count	2
精确质量Exact Mass	139.04 Da
单同位素质量Monoisotopic Mass	139.04 Da
拓扑极表面积Topological Polar Surface Area	52.300 Å²
重原子数Heavy Atom Count	8
形式电荷Formal Charge	0
复杂度Complexity	72.100
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	2

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany	3
个人防护装备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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找到21个结果

批号(Lot Number)	证书类型	货号
C2211105	分析证书	A100815
I2315118	分析证书	A100815
B2321082	分析证书	A100815
B2321079	分析证书	A100815
B2321071	分析证书	A100815
F2421081	分析证书	A100815
F2421082	分析证书	A100815
F2421083	分析证书	A100815
C2531054	分析证书	A100815
F2421080	分析证书	A100815
D2403687	分析证书	A100815
D2403651	分析证书	A100815
C2211096	分析证书	A100815
C2211106	分析证书	A100815
C2211125	分析证书	A100815
C1823078	分析证书	A100815
F2118011	分析证书	A100815
F2117073	分析证书	A100815
F2118002	分析证书	A100815
K2329221	分析证书	A100815
C2412069	分析证书	A100815

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此产品的引用文献

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引用文献

1. B J Bogitsh,G R Davenport. (1991-04-01) The in vitro effects of various lysosomotropic agents on the gut of Schistosoma mansoni schistosomula.. The Journal of parasitology, 77 ((2)): (187-193). [PMID:2010852]
2. Katarzyna Guzow,Magda Milewska,Wiesław Wiczk. (2005-03-03) Solvatochromism of 3-[2-(4-diphenylaminophenyl)benzoxazol-5-yl]alanine methyl ester. A new fluorescence probe.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 61 ((6)): (1133-1140). [PMID:15741112]
3. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein. (2008-12-09) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.. Nature chemical biology, 5 ((1)): (45-52). [PMID:19060912]
4. Erik Schwartz,Pavol Bodis,Matthieu Koepf,Jeroen J L M Cornelissen,Alan E Rowan,Sander Woutersen,Roeland J M Nolte. (2009-07-31) Self-trapped vibrational states in synthetic beta-sheet helices.. Chemical communications (Cambridge, England), ((31)): (4675-4677). [PMID:19641806]
5. Bing Shi Li,Jacky W Y Lam,Zhen-Qiang Yu,Ben Zhong Tang. (2012-03-15) Tunable helical assemblies of L-alanine methyl ester-containing polyphenylacetylene.. Langmuir : the ACS journal of surfaces and colloids, 28 ((13)): (5770-5774). [PMID:22413849]
6. Jeanette Kheir,Lidia Chomicz,Alyson Engle,Janusz Rak,Michael D Sevilla. (2013-02-15) Presolvated low energy electron attachment to peptide methyl esters in aqueous solution: C-O bond cleavage at 77 K.. The journal of physical chemistry. B, 117 ((10)): (2872-2877). [PMID:23406302]
7. Josef Dib,Nils Schlörer,Wilhelm Schänzer,Mario Thevis. (2015-03-25) Studies on the collision-induced dissociation of adipoR agonists after electrospray ionization and their implementation in sports drug testing.. Journal of mass spectrometry : JMS, 50 ((2)): (407-417). [PMID:25800023]
8. Jose Manuel Ageitos,Kenjiro Yazawa,Ayaka Tateishi,Kousuke Tsuchiya,Keiji Numata. (2015-12-02) The Benzyl Ester Group of Amino Acid Monomers Enhances Substrate Affinity and Broadens the Substrate Specificity of the Enzyme Catalyst in Chemoenzymatic Copolymerization.. Biomacromolecules, 17 ((1)): (314-323). [PMID:26620763]
9. Peter G W Gettins,Klavs Dolmer. (2011-12-21) A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein).. The Biochemical journal, 443 ((1)): (65-73). [PMID:22181833]
10. Hala Bakr El-Nassan,Aliaa Nabil ElMeshad,Walaa Wadie,Rabab H Sayed. (2018-05-31) Synthesis, Characterization and Biocompatibility of N-palmitoyl L-alanine-based Organogels as Sustained Implants of Granisetron and Evaluation of thier Antiemetic Effect.. Pharmaceutical research, 35 ((8)): (149-149). [PMID:29845459]
11. Beibei Hu,Wei Sun,Baixue Yang,Heran Li,Liuchenzi Zhou,Sanming Li. (2018-05-31) Application of Solvent Parameters for Predicting Organogel Formation.. AAPS PharmSciTech, 19 ((5)): (2288-2300). [PMID:29845502]
12. Beibei Hu,Haipeng Yan,Yanping Sun,Xi Chen,Yujuan Sun,Sanming Li,Yongshuai Jing,Heran Li. (2019-12-19) Organogels based on amino acid derivatives and their optimization for drug release using response surface methodology.. Artificial cells, nanomedicine, and biotechnology, 48 ((1)): (266-275). [PMID:31851842]
13. Luyao Zheng, Zhiyuan Zhao, Ye Yang, Yaming Li, Chengxiao Wang. (2020) Novel skin permeation enhancers based on amino acid ester ionic liquid: Design and permeation mechanism. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 576 (119031). [PMID:31953082] [10.1016/j.ijpharm.2020.119031]
14. Yumei Wang, Jia Ke, Kaijun Gou, Yingyu Guo, Xiaomin Xu, Sanming Li, Heran Li. (2020) Amino functionalized mesoporous silica with twisted rod-like shapes: Synthetic design, in vitro and in vivo evaluation for ibuprofen delivery. MICROPOROUS AND MESOPOROUS MATERIALS, 294 (109896). [10.1016/j.micromeso.2019.109896]
15. Nabila Mehwish, Ayesha Kousar, Auphedeous Yinme Dang-i, Juexin Huang, Xiaoqiu Dou, Chuanliang Feng. (2019) Molecular recognition of melamine and cyanuric acid by C2-symmetric phenylalanine based supramolecular hydrogels. EUROPEAN POLYMER JOURNAL, 118 (170). [10.1016/j.eurpolymj.2019.05.059]
16. A. Kousar, J. Liu, N. Mehwish, F. Wang, A.Y. Dang-i, C. Feng. (2019) pH-Regulated supramolecular chirality of phenylalanine-based hydrogels. Materials Today Chemistry, 11 (217). [10.1016/j.mtchem.2018.11.005]
17. Shilei Ji, Nan Li, Yong Shen, Qi Li, Juan Qiao, Zhibo Li. (2016) Poly(amino acid)-based thermoresponsive molecularly imprinted magnetic nanoparticles for specific recognition and release of lysozyme. ANALYTICA CHIMICA ACTA, 909 (60). [PMID:26851085] [10.1016/j.aca.2016.01.005]
18. Yumei Wang,Wei Li,Tiaotiao Liu,Lu Xu,Yingyu Guo,Jia Ke,Sanming Li,Heran Li. (2019-07-28) Design and preparation of mesoporous silica carriers with chiral structures for drug release differentiation.. Materials science & engineering. C, Materials for biological applications, 103 (109737-109737). [PMID:31349514]
19. Jiaxuan Wang, Cuiping Pang, Zhonglin Tu, Jianghua Li, Guocheng Du, Guoqiang Zhang. (2024) Double enzymes coupled screening assisted molecular modification of α-Amino acid ester acyltransferase for L-Alanyl-l-Glutamine biosynthesis. Food Bioscience, 58 (103643). [10.1016/j.fbio.2024.103643]

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货号 (SKU)	包装规格	是否现货
A100815-5g	5g	现货
A100815-10g	10g	现货
A100815-25g	25g	现货
A100815-100g	100g	现货
A100815-500g	500g	现货

L-丙氨酸甲酯盐酸盐

库存信息

库存信息

库存信息

库存信息

库存信息

基本描述

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

显示更多⌵

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器