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4-氨基-3-肼基-5-巯基-1,2,4-三唑

12篇引用文献 COA COA
    级别和纯度:
  • AR
    •
  • ≥95%
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货号 (SKU) 包装规格 是否现货 价格 数量
A100781-1g
 1g 现货 Stock Image
A100781-5g
 5g 现货 Stock Image
A100781-25g
 25g 期货 Stock Image
A100781-100g
 100g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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光谱试剂 (247) 无卤杂环砌块 (1210) 环保试剂 (41)
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基本描述

别名 4-氨基-5-肼基-1,2,4-三唑-3-硫醇 (AHMT)
英文别名 4-Amino-5-hydrazino-1,2,4-triazole-3-thiol
规格或纯度 AR, ≥95%
英文名称 4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole(AHMT)
储存温度 -20°C储存
运输条件 超低温冰袋运输
产品介绍

测定甲醛和其它反应性化学品的专一试剂。HPLC中衍生中性单糖。

for Determination of Aldehydes


Application：

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole is a reagent used in the determination of aldehydes and other reactive chemicals.was used in purpald assay for determination of bacterial polysaccharides containing substituted or unsubstituted glycol in residues such as glycerol, ribitol, arabinitol, furanosyl galactose and sialic acid. It was used as chromogen during the determination of catalase activity in small tissue samples. It was used as reagent in determination of formaldehyde. It was used for derivatization of neutral monosaccharides during HPLC.
纯度 ≥95%

关联靶点（人）

ALDOA Tbio Fructose-bisphosphate aldolase A (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GAPDH Tchem Glyceraldehyde-3-phosphate dehydrogenase liver (1284 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HEK293 (82097 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HepG2 (196354 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLI Tchem DNA polymerase iota (116820 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APOBEC3F Tbio DNA dC->dU-editing enzyme APOBEC-3F (14861 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
dnaB Replicative DNA helicase (15 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
recA Protein RecA (2211 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 217-135-8
分子类型 小分子
IIUPAC Name 4-amino-3-hydrazinyl-1H-1,2,4-triazole-5-thione
INCHI 1S/C2H6N6S/c3-5-1-6-7-2(9)8(1)4/h3-4H2,(H,5,6)(H,7,9)
InChi Key RDIMQHBOTMWMJA-UHFFFAOYSA-N
Smiles C1(=S)NN=C(N1N)NN
Isomeric SMILES C1(=S)NN=C(N1N)NN
UN Number 1325
分子量 146.17
Beilstein号 134867
Reaxy-Rn 144338
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=144338&ln=

化学和物理性质

溶解性 Soluble in Dimethyl sulfoxide.(DMSO)
密度 2.31
熔点 220-240℃
分子量 146.180 g/mol
XLogP3 -1.100
氢键供体数Hydrogen Bond Donor Count 4
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 1
精确质量Exact Mass 146.037 Da
单同位素质量Monoisotopic Mass 146.037 Da
拓扑极表面积Topological Polar Surface Area 124.000 Ų
重原子数Heavy Atom Count 9
形式电荷Formal Charge 0
复杂度Complexity 162.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS02
信号词 警告
危险声明

H228: 易燃固体

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。

P240: 地面/粘结容器和接收设备

P241: 使用防爆的[电气/通风/照明/.../]设备。

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P370+P378: 火灾时：使用干砂、干粉或抗醇泡沫灭火。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到29个结果

批号(Lot Number) 证书类型 货号
G2522195 分析证书 A100781
G2522196 分析证书 A100781
G2522197 分析证书 A100781
G2424314 分析证书 A100781
G2424315 分析证书 A100781
G2424316 分析证书 A100781
D2415006 分析证书 A100781
D2415007 分析证书 A100781
D2415171 分析证书 A100781
D2415172 分析证书 A100781
D2415173 分析证书 A100781
H2328096 分析证书 A100781
H2328097 分析证书 A100781
H2328098 分析证书 A100781
H2328103 分析证书 A100781
H2328105 分析证书 A100781
H2328106 分析证书 A100781
C2429075 分析证书 A100781
H2328108 分析证书 A100781
H2328110 分析证书 A100781
E2317293 分析证书 A100781
E2317295 分析证书 A100781
E2317292 分析证书 A100781
E2317288 分析证书 A100781
G2226095 分析证书 A100781
G2226096 分析证书 A100781
G2226100 分析证书 A100781
G2226103 分析证书 A100781
K2210213 分析证书 A100781

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引用文献

1. Dan Huo, Xipeng Zhang, Jiaxin Wei, Jinhua Wang, Qiang Zhang, Qiulin Yang, Hongxiang Zhu, Fengshan Zhang, Guigan Fang, Ting Wu.  (2023)  Preparation and characterization of cellulose nanofibril/chitosan aerogels with high-adsorbability and sensitive indication for indoor free formaldehyde.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  (128891).  [PMID:38143065] [10.1016/j.ijbiomac.2023.128891]
2. Yang Xiaozheng, Liu Yusong, Huang Jing, Tao Ye, Wang Yifeng, Shen Renfang, Zhu Xiaofang.  (2023)  NaCl Facilitates Cell Wall Phosphorus Reutilization in Abscisic Acid Dependent Manner in Phosphorus Deficient Rice Root.  Rice Science,  30  (138).  [10.1016/j.rsci.2023.01.006]
3. Qi Nie, Jingjing Deng, Bing Xie, Guoyue Shi, Tianshu Zhou.  (2021)  A dual-channel colorimetric and fluorescent sensor for the rapid and ultrasensitive detection of kanamycin based on gold nanoparticles-copper nanoclusters.  Analytical Methods,  13  (48): (5813-5820).  [PMID:34852031] [10.1039/D1AY01460A]
4. Kun Ge, Lunzhao Yi, Qiyue Wu, Yonghui Li, Hanqiang Zhang, Ying Gu.  (2021)  Detection of Formaldehyde by Surface-Enhanced Raman Spectroscopy Based on PbBiO2Br/Au4Ag4 Nanospheres.  ACS Applied Nano Materials,  4  (10): (10218–10227).  [10.1021/acsanm.1c01710]
5. Lu Feng, Tianyu Zeng, Haobo Hou.  (2021)  Post-functionalized metal−organic framework for effective and selective removal of Hg(II) in aqueous media.  MICROPOROUS AND MESOPOROUS MATERIALS,  328  (111479).  [10.1016/j.micromeso.2021.111479]
6. Biao Zeng, Wei Wang, Sijin He, Guo Lin, Wenjia Du, Jun Chang, Zhao Ding.  (2021)  Facile synthesis of zinc-based organic framework for aqueous Hg (II) removal: Adsorption performance and mechanism.  Nano Materials Science,  3  (429).  [10.1016/j.nanoms.2021.06.005]
7. Guo Lei, Wu Min, Leng Senlin, Qiang Yujie, Zheng Xingwen.  (2018)  Synergistic Effect of Purpald with Tartaric Acid on the Corrosion Inhibition of Mild Steel: from Electrochemical to Theoretical Insights.  Protection of Metals and Physical Chemistry of Surfaces,  54  (5): (917-925).  [10.1134/S2070205118050076]
8. Zhang Dandan, Li Jing, Su Zhen, Hu Sanyuan, Li Heping, Yan Youwei.  (2018)  Electrospun polyporous VN nanofibers for symmetric all-solid-state supercapacitors.  Journal of Advanced Ceramics,  7  (3): (246-255).  [10.1007/s40145-018-0276-2]
9. Ren-Jie Li, Jian-He Xu, Yue-Cai Yin, Nicolas Wirth, Jiang-Meng Ren, Bu-Bing Zeng, Hui-Lei Yu.  (2016)  Rapid probing of the reactivity of P450 monooxygenases from the CYP116B subfamily using a substrate-based method.  NEW JOURNAL OF CHEMISTRY,  40  (10): (8928-8934).  [10.1039/C6NJ00809G]
10. Feng Yu, Yu-Long Jia, Hui-Fang Wang, Jing Zheng, Yi Cui, Xin-Yu Fang, Lin-Min Zhang, Qing-Xi Chen.  (2015)  Synthesis of Triazole Schiff’s Base Derivatives and Their Inhibitory Kinetics on Tyrosinase Activity.  PLoS One,  10  (9): (e0138578).  [PMID:26422245] [10.1371/journal.pone.0138578]
11. Wang Ai-Jun, Guo Han, Zhang Ming, Zhou Dan-Ling, Wang Rui-Zhi, Feng Jiu-Ju.  (2013)  Sensitive and selective colorimetric detection of cadmium(II) using gold nanoparticles modified with 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole.  MICROCHIMICA ACTA,  180  (11): (1051-1057).  [10.1007/s00604-013-1030-7]
12. Xi Zhu, Yong Guo, Baozhan Zheng.  (2024)  Preparation of 4-Amino-3-hydrazino-1,2,4-triazol-5-thiol-Modified Graphene Oxide and Its Greatly Enhanced Selective Adsorption of Gallium in Aqueous Solution.  MOLECULES,  29  (12): (2778).  [PMID:38930842] [10.3390/molecules29122778]

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