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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176075-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$79.90
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Ab176075-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$389.90
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Ab176075-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$959.90
|
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Ab176075-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,529.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Vorsetuzumab (anti-CD70) - Primary antibody, specific to CD70, >95%, high purity, Human IgG1, BINDING AGENT of CD70 antigen binding agent |
|---|---|
| Synonyms | CD 27L antibody | CD 70 antibody | CD27 L antibody | CD27 LG antibody | CD27 ligand antibody | CD27-L antibody | CD27L antibody | CD27LG antibody | CD70 antibody | CD70 antigen antibody | CD70 molecule antibody | CD70_HUMAN antibody | Ki 24 antigen antibo |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD70 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of CD70 antigen binding agent |
| Product Description |
Vorsetuzumab (anti-CD70) is a human anti-CD70 antibody. Vorsetuzumab (anti-CD70) enhances macrophage-related phagocytosis of renal carcinoma cells, shows inhibitory efficacy against Burkitt’s lymphoma. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.1 kDa (Light Chain) & 52.6 kDa (Heavy Chain), under reducing conditions; 180.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1165740-62-4 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Vorsetuzumab (anti-CD70) (Ab176075) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD70 (red) with Vorsetuzumab (anti-CD70) (Ab176075). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vorsetuzumab (anti-CD70) (Ab176075) - SEC
The purity of Vorsetuzumab (anti-CD70) (Ab176075) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 13, 2023 | Ab176075 | |
| Certificate of Analysis | Oct 13, 2023 | Ab176075 |
Starting at $69.90