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Vorsetuzumab (anti-CD70) - Primary antibody, specific to CD70, >95%, high purity, Human IgG1, BINDING AGENT of CD70 antigen binding agent, BINDING AGENT of CD70 antigen binding agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176075
Grouped product items
SKU Size
Availability
Price Qty
Ab176075-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab176075-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$389.90
Ab176075-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$959.90
Ab176075-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,529.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Vorsetuzumab (anti-CD70) - Primary antibody, specific to CD70, >95%, high purity, Human IgG1, BINDING AGENT of CD70 antigen binding agent
Synonyms CD 27L antibody | CD 70 antibody | CD27 L antibody | CD27 LG antibody | CD27 ligand antibody | CD27-L antibody | CD27L antibody | CD27LG antibody | CD70 antibody | CD70 antigen antibody | CD70 molecule antibody | CD70_HUMAN antibody | Ki 24 antigen antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD70
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of CD70 antigen binding agent
Product Description

Vorsetuzumab (anti-CD70) is a human anti-CD70 antibody. Vorsetuzumab (anti-CD70) enhances macrophage-related phagocytosis of renal carcinoma cells, shows inhibitory efficacy against Burkitt’s lymphoma.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.1 kDa (Light Chain) & 52.6 kDa (Heavy Chain), under reducing conditions; 180.8 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1165740-62-4

Associated Targets(Human)

CD70 Tbio CD70 antigen (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Vorsetuzumab (anti-CD70) (Ab176075) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD70 (red) with Vorsetuzumab (anti-CD70) (Ab176075). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Vorsetuzumab (anti-CD70) (Ab176075) - SEC
The purity of Vorsetuzumab (anti-CD70) (Ab176075) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001277 Certificate of Analysis Oct 13, 2023 Ab176075
ZJ23F1001278 Certificate of Analysis Oct 13, 2023 Ab176075

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