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Cusatuzumab (anti-CD70) - Primary antibody, specific to CD70, >95%, high purity, Human IgG1, INHIBITOR of CD70 antigen inhibitor, INHIBITOR of CD70 antigen inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170844
Grouped product items
SKU Size
Availability
Price Qty
Ab170844-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab170844-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$327.90
Ab170844-5mg
5mg
2
$687.90
Ab170844-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,107.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Cusatuzumab (anti-CD70) - Primary antibody, specific to CD70, >95%, high purity, Human IgG1, INHIBITOR of CD70 antigen inhibitor
Synonyms CD 27L antibody | CD 70 antibody | CD27 L antibody | CD27 LG antibody | CD27 ligand antibody | CD27-L antibody | CD27L antibody | CD27LG antibody | CD70 antibody | CD70 antigen antibody | CD70 molecule antibody | CD70_HUMAN antibody | Ki 24 antigen antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD70
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of CD70 antigen inhibitor
Product Description

Cusatuzumab (anti-CD70) is a human αCD70 monoclonal antibody. Cusatuzumab (anti-CD70) shows cytotoxicity activity with enhanced antibody-dependent cellular. Cusatuzumab (anti-CD70) reduces leukemia stem cells (LSCs) and triggers gene signatures related to myeloid differentiation and apoptosis. Cusatuzumab (anti-CD70) has the potential for the research of Acute myeloid leukemia (AML).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type lambdaC2
SDS-PAGE 27.5 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 170.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1864871-20-4

Associated Targets(Human)

CD70 Tbio CD70 antigen (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607381 Certificate of Analysis Jun 26, 2024 Ab170844
ZJ23F1001417 Certificate of Analysis Oct 26, 2023 Ab170844
ZJ23F1001418 Certificate of Analysis Oct 26, 2023 Ab170844

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