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trans-4-(Aminomethyl)cyclohexanecarboxylic acid - 98%, high purity , CAS No.1197-18-8

5 Citations

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 1197-18-8
Molecular Weight: 157.21
MDL number: MFCD00001466
PubChem CID: 5526
PubChem SID: 488179908

In stock

Item Number

A111900

Grouped product items
SKU	Size	Availability	Price
A111900-5g	5g	3	$26.90
A111900-10g	10g	1	$39.90
A111900-25g	25g	1	$57.90
A111900-50g	50g	1	$92.90
A111900-100g	100g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$161.90
A111900-250g	250g	2	$259.90
A111900-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$414.90

Antifibrinolytic and plasminogen activation inhibitor

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Basic Description

Synonyms	tranexamic acid \| AMCA \| Cyklokapron \| trans-4-(Aminomethyl)cyclohexanecarboxylic acid \| cyclocapron
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Antifibrinolytic and plasminogen activation inhibitor. Blocks lysine-binding sites of plasmin and elastase-derived plasminogen fragments (IC 50 = 5 mM).
Shipped In	Normal
Grade	Moligand™
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Inhibits plasmin-induced fibrinolysis

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Amino acids

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives
Direct Parent	Amino acids
Alternative Parents	Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic homomonocyclic compounds
Substituents	Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Aliphatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as amino acids. These are organic compounds that contain at least one carboxyl group and one amino group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

PLG Tclin Plasminogen (0 Activities)

Discover Target: PLG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488179908
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488179908
IUPAC Name	4-(aminomethyl)cyclohexane-1-carboxylic acid
INCHI	InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)
InChIKey	GYDJEQRTZSCIOI-UHFFFAOYSA-N
Smiles	NC[C@H]1CC[C@@H](CC1)C(O)=O
Isomeric SMILES	C1CC(CCC1CN)C(=O)O
WGK Germany	2
Molecular Weight	157.21
Reaxy-Rn	2207452
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2207452&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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27 results found

Lot Number	Certificate Type	Date	Item
B2510156	Certificate of Analysis	Jan 08, 2025	A111900
B2510157	Certificate of Analysis	Jan 08, 2025	A111900
B2510158	Certificate of Analysis	Jan 08, 2025	A111900
B2510159	Certificate of Analysis	Jan 08, 2025	A111900
B2510160	Certificate of Analysis	Jan 08, 2025	A111900
A2515197	Certificate of Analysis	Jul 23, 2024	A111900
G2410005	Certificate of Analysis	Jun 05, 2024	A111900
G2410006	Certificate of Analysis	Jun 05, 2024	A111900
G2410045	Certificate of Analysis	Jun 05, 2024	A111900
F2427092	Certificate of Analysis	Jun 05, 2024	A111900
F2427090	Certificate of Analysis	Apr 25, 2024	A111900
L2327030	Certificate of Analysis	Feb 11, 2023	A111900
C2302035	Certificate of Analysis	Feb 11, 2023	A111900
C2302112	Certificate of Analysis	Feb 11, 2023	A111900
C2302778	Certificate of Analysis	Feb 11, 2023	A111900
C2302113	Certificate of Analysis	Feb 11, 2023	A111900
C2302028	Certificate of Analysis	Feb 11, 2023	A111900
C2302102	Certificate of Analysis	Feb 11, 2023	A111900
C2302029	Certificate of Analysis	Feb 11, 2023	A111900
C2302030	Certificate of Analysis	Feb 11, 2023	A111900
C2302103	Certificate of Analysis	Feb 11, 2023	A111900
C2302036	Certificate of Analysis	Feb 11, 2023	A111900
C2302038	Certificate of Analysis	Feb 11, 2023	A111900
C2302039	Certificate of Analysis	Feb 11, 2023	A111900
C2302041	Certificate of Analysis	Feb 11, 2023	A111900
F2327390	Certificate of Analysis	Feb 11, 2023	A111900
A2424006	Certificate of Analysis	Feb 11, 2023	A111900

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Chemical and Physical Properties

Solubility	Soluble in water (167 mg/ml), ethanol (<1 mg/ml at 25°C).Very slightly soluble in ether, DMSO (<1 mg/ml at 25°C), and alcohol.
Molecular Weight	157.210 g/mol
XLogP3	-2.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	157.11 Da
Monoisotopic Mass	157.11 Da
Topological Polar Surface Area	63.300 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	139.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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