Skip to the beginning of the images gallery

TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] - >97.0%(N), [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC], high purity , CAS No.36951-72-1

1 Citations

COA

Grade & Purity:

≥97%(N)

Cas Number: 36951-72-1
Molecular Weight: 1363.6
MDL number: MFCD00013468

In stock

Item Number

T162409

Grouped product items
SKU	Size	Availability	Price
T162409-100mg	100mg	5	$57.90
T162409-250mg	250mg	2	$109.90
T162409-1g	1g	1	$299.90

Telomerase inhibitor. Binds and stabilizes DNA G-quadruplexes.

View related series

Anti-infection (2803) Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Cholinesterase (ChE) (151) G-quadruplex (18) Neuronal Signaling (3320) p-Toluenesulfonates (1) SARS-CoV (200) Six-Membered Heterocyclic Compounds (1696) Spectroscopic reagent (233) Telomerase (21) telomerase inhibitor (1) Virus (1811)

Basic Description

Synonyms	TMPyP \| 5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate) \| α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate
Specifications & Purity	≥97%(N)
Biochemical and Physiological Mechanisms	Cationic porphyrin. Telomerase inhibitor (IC 50 = 6.5 µM). Binds and stabilizes DNA G quadruplexes resulting in telomerase inhibition. Displays antitumor effect.
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent 1O2 luminescence signals on incubation with the fungus, Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer. TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] (TMPyP), a cationic porphyrin, was used to study the noncovalent functionalization of graphene with cationic porphyrins using UV-vis and fluorescence methods. TMPyP may be used as an optical indicator ligand in the preparation of multifunctional membrane for visual warning and enhanced adsorptive removal of cadmium ions in aqueous solutions. TMPyP was also used to fabricate the (TMPyP)- single-walled carbon nanotubes (SWNT)/sodium copper chlorophyllin-SWNT layer-by-layer film from noncovalently adsorbed composites.

Names and Identifiers

Molecular Weight	1363.6
Reaxy-Rn	5237096

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
E2519447	Certificate of Analysis	Apr 02, 2025	T162409
E2519469	Certificate of Analysis	Apr 02, 2025	T162409
E2519470	Certificate of Analysis	Apr 02, 2025	T162409
D23081526	Certificate of Analysis	Feb 25, 2023	T162409
D23081527	Certificate of Analysis	Feb 25, 2023	T162409
D23081523	Certificate of Analysis	Feb 25, 2023	T162409
D23081578	Certificate of Analysis	Feb 25, 2023	T162409
D23081528	Certificate of Analysis	Feb 25, 2023	T162409
D23081618	Certificate of Analysis	Feb 25, 2023	T162409
C2518079	Certificate of Analysis	Feb 25, 2023	T162409

Chemical and Physical Properties

Solubility	water: soluble 50 mM(lit.)
Sensitivity	Light & Moisture Sensitive

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] - >97.0%(N), [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC], high purity , CAS No.36951-72-1

Basic Description

Names and Identifiers

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Chemical and Physical Properties

Alternative Products

Citations of This Product

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reviews

Customer Reviews