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Targets(Human)
TRPV4

TRPV4

Description	Transient receptor potential cation channel subfamily V member 4

Gene and Protein Information

Gene ID	59341
Uniprot Accession IDs	Q9HBA0 B7ZKQ6 Q17R79 Q2Y122 Q2Y123 Q2Y124 Q86YZ6 Q8NDY7 Q8NG64 Q96Q92 Q96RS7 Q9HBC0 TrpV4
Ensembl ID	ENSG00000111199
Symbol	VRL2 VROAC SMAL VRL2 BCYM3 CMT2C SPSMA TRP12 VROAC HMSN2C OTRPC4 SSQTL1
Chromosome	12
Family	Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV4 sub-subfamily.
Sequence	MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDNKRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	452225	TRPV4	transient receptor potential cation channel subfamily V member 4	9598	VGNC:8587	OMA, EggNOG
Macaque	709605	TRPV4	transient receptor potential cation channel subfamily V member 4	9544		Inparanoid, OMA, EggNOG
Mouse	63873	Trpv4	transient receptor potential cation channel, subfamily V, member 4	10090	MGI:1926945	Inparanoid, OMA, EggNOG
Rat	66026	Trpv4	transient receptor potential cation channel, subfamily V, member 4	10116	RGD:69337	Inparanoid, OMA, EggNOG
Horse	100066552	TRPV4	transient receptor potential cation channel subfamily V member 4	9796	VGNC:24567	Inparanoid, OMA
Cow	540259	TRPV4	transient receptor potential cation channel subfamily V member 4	9913	VGNC:36400	Inparanoid, OMA
Xenopus	100496204	trpv4	transient receptor potential cation channel, subfamily V, member 4	8364	XB-GENE-998899	Inparanoid, OMA
Zebrafish	557850	trpv4	transient receptor potential cation channel, subfamily V, member 4	7955	ZDB-GENE-030912-7	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / transporter / ion channel / Transient receptor potential cation channel subfamily V member 4

DTO Classes
protein / Ion channel / Transient receptor potential calcium channel (TRP-CC) family / TrpV subfamily / TRPV4 sub-subfamily / Transient receptor potential cation channel subfamily V member 4

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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