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| Description | Receptor tyrosine-protein kinase erbB-3 |
|---|
Gene and Protein Information
| Gene ID | 2065 |
|---|---|
| Uniprot Accession IDs | P21860 A8K6L6 B4DIK7 B4DV32 E9PDT8 Q9BUD7 |
| Ensembl ID | ENSG00000065361 |
| Symbol | HER3 HER3 FERLK LCCS2 ErbB-3 c-erbB3 erbB3-S MDA-BF-1 c-erbB-3 p180-ErbB3 p45-sErbB3 p85-sErbB3 |
| Chromosome | 12 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. |
| Sequence |
MRANDALQVLGLLFSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRESGPGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDNLATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGESCQESAVSGSSERCPRPVSLHPMPRGCLASESSEGHVTGSEAELQEKVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLEEEDVNGYVMPDTHLKGTPSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRRRRHSPPHPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIMPTAGTTPDEDYEYMNRQRDGGGPGGDYAAMGACPASEQGYEEMRAFQGPGHQAPHVHYARLKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | RPS26 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 9544 | OMA, EggNOG | ||
| Mouse | 13867 | Erbb3 | erb-b2 receptor tyrosine kinase 3 | 10090 | MGI:95411 | Inparanoid, OMA, EggNOG |
| Rat | 29496 | Erbb3 | erb-b2 receptor tyrosine kinase 3 | 10116 | RGD:69323 | Inparanoid, OMA, EggNOG |
| Dog | 481105 | ERBB3 | erb-b2 receptor tyrosine kinase 3 | 9615 | VGNC:54147 | Inparanoid, OMA, EggNOG |
| Horse | 100059216 | ERBB3 | erb-b2 receptor tyrosine kinase 3 | 9796 | VGNC:17650 | Inparanoid, OMA, EggNOG |
| Cow | 785655 | ERBB3 | erb-b2 receptor tyrosine kinase 3 | 9913 | VGNC:28564 | Inparanoid, OMA, EggNOG |
| Opossum | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 13616 | Inparanoid, OMA, EggNOG | ||
| Anole lizard | 100556326 | erbb3 | erb-b2 receptor tyrosine kinase 3 | 28377 | Inparanoid, OMA | |
| Xenopus | 100493384 | erbb3 | erb-b2 receptor tyrosine kinase 3 | 8364 | XB-GENE-853369 | Inparanoid, OMA, EggNOG |
| Zebrafish | 544664 | erbb3b | erb-b2 receptor tyrosine kinase 3b | 7955 | ZDB-GENE-050107-1 | Inparanoid, OMA |
| C. elegans | 174462 | let-23 | Receptor protein-tyrosine kinase | 6239 | OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / EGFR family / Receptor tyrosine-protein kinase erbb-3
protein / Kinase / Protein kinase / TK group / EGFR family / Receptor tyrosine-protein kinase erbb-3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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