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| Description | Sodium-dependent serotonin transporter |
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Gene and Protein Information
| Gene ID | 6532 |
|---|---|
| Uniprot Accession IDs | P31645 Q5EE02 SERT |
| Ensembl ID | ENSG00000108576 |
| Symbol | HTT SERT HTT 5HTT OCD1 SERT 5-HTT SERT1 hSERT 5-HTTLPR |
| Chromosome | 17 |
| Family | Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily. |
| Sequence |
METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 468201 | SLC6A4 | solute carrier family 6 member 4 | 9598 | VGNC:9626 | OMA, EggNOG |
| Macaque | 574140 | SLC6A4 | solute carrier family 6 member 4 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 15567 | Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 10090 | MGI:96285 | Inparanoid, OMA, EggNOG |
| Rat | 25553 | Slc6a4 | solute carrier family 6 member 4 | 10116 | RGD:3714 | Inparanoid, OMA, EggNOG |
| Dog | 491184 | SLC6A4 | solute carrier family 6 member 4 | 9615 | VGNC:46465 | Inparanoid, OMA, EggNOG |
| Horse | 100033848 | SLC6A4 | solute carrier family 6 member 4 | 9796 | VGNC:23261 | OMA, EggNOG |
| Cow | 282365 | SLC6A4 | solute carrier family 6 member 4 | 9913 | VGNC:49971 | Inparanoid, OMA, EggNOG |
| Pig | 100517307 | SLC6A4 | solute carrier family 6 member 4 | 9823 | OMA, EggNOG | |
| Opossum | 100015330 | SLC6A4 | solute carrier family 6 member 4 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 404747 | SLC6A4 | solute carrier family 6 member 4 | 9031 | CGNC:3120 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100562250 | slc6a4 | solute carrier family 6 member 4 | 28377 | Inparanoid, OMA, EggNOG | |
| Zebrafish | 664719 | slc6a4a | solute carrier family 6 (neurotransmitter transporter), member 4a | 7955 | ZDB-GENE-060314-1 | Inparanoid, OMA |
| C. elegans | 171879 | mod-5 | Transporter | 6239 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Monoamine transporter subfamily / Sodium-dependent serotonin transporter
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Monoamine transporter subfamily / Sodium-dependent serotonin transporter
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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