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| Description | Solute carrier family 12 member 3 |
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Gene and Protein Information
| Gene ID | 6559 |
|---|---|
| Uniprot Accession IDs | P55017 A8MSJ2 C9JNN9 |
| Ensembl ID | ENSG00000070915 |
| Symbol | NCC TSC NCC TSC NCCT |
| Chromosome | 16 |
| Family | Belongs to the SLC12A transporter family. |
| Sequence |
MAELPTTETPGDATLCSGRFTISTLLSSDEPSPPAAYDSSHPSHLTHSSTFCMRTFGYNTIDVVPTYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIAVVSVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVVRDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQINRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEITKNRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLSQDLRPPVILIRGNQENVLTFYCQ
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 454108 | SLC12A3 | solute carrier family 12 member 3 | 9598 | VGNC:9011 | OMA, EggNOG |
| Macaque | 703090 | SLC12A3 | solute carrier family 12 member 3 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20497 | Slc12a3 | solute carrier family 12, member 3 | 10090 | MGI:108114 | Inparanoid, OMA, EggNOG |
| Rat | 54300 | Slc12a3 | solute carrier family 12 member 3 | 10116 | RGD:3686 | Inparanoid, OMA |
| Dog | 478118 | SLC12A3 | solute carrier family 12 member 3 | 9615 | VGNC:46220 | Inparanoid, OMA, EggNOG |
| Horse | 100051953 | SLC12A3 | solute carrier family 12 member 3 | 9796 | VGNC:51307 | Inparanoid, OMA, EggNOG |
| Cow | 404171 | SLC12A3 | solute carrier family 12 member 3 | 9913 | VGNC:34666 | Inparanoid, OMA, EggNOG |
| Opossum | 100015656 | SLC12A3 | solute carrier family 12 member 3 | 13616 | Inparanoid, EggNOG | |
| Chicken | 415692 | SLC12A3 | solute carrier family 12 member 3 | 9031 | CGNC:2136 | Inparanoid, OMA |
| Anole lizard | 100562387 | slc12a3 | solute carrier family 12 member 3 | 28377 | OMA, EggNOG | |
| Xenopus | 100494755 | slc12a3 | solute carrier family 12 member 3 | 8364 | XB-GENE-866805 | Inparanoid, OMA |
| Zebrafish | 565439 | slc12a3 | solute carrier family 12 (sodium/chloride transporter), member 3 | 7955 | ZDB-GENE-030131-9505 | Inparanoid, OMA, EggNOG |
| C. elegans | 3565648 | nkcc-1 | Na-K-Cl Cotransporter homolog | 6239 | Inparanoid, EggNOG |
Protein Classes
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC12 family of cation-coupled chloride transporters / Solute carrier family 12 member 3
protein / Transporter / SLC superfamily of solute carriers / SLC12 family of cation-coupled chloride transporters / Solute carrier family 12 member 3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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