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| Description | Sodium-dependent dopamine transporter |
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Gene and Protein Information
| Gene ID | 6531 |
|---|---|
| Uniprot Accession IDs | Q01959 A2RUN4 Q14996 DA transporter |
| Ensembl ID | ENSG00000142319 |
| Symbol | DAT1 DAT DAT1 PKDYS PKDYS1 |
| Chromosome | 5 |
| Family | Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily. |
| Sequence |
MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 750842 | SLC6A3 | solute carrier family 6 member 3 | 9598 | VGNC:50806 | OMA, EggNOG |
| Macaque | 574143 | SLC6A3 | solute carrier family 6 member 3 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 13162 | Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 10090 | MGI:94862 | Inparanoid, OMA, EggNOG |
| Rat | 24898 | Slc6a3 | solute carrier family 6 member 3 | 10116 | RGD:3715 | Inparanoid, OMA, EggNOG |
| Dog | 609304 | SLC6A3 | solute carrier family 6 member 3 | 9615 | VGNC:46464 | Inparanoid, OMA, EggNOG |
| Horse | 100054747 | SLC6A3 | solute carrier family 6 member 3 | 9796 | VGNC:23260 | Inparanoid, OMA, EggNOG |
| Pig | 100521346 | SLC6A3 | solute carrier family 6 member 3 | 9823 | OMA, EggNOG | |
| Opossum | 100015498 | SLC6A3 | solute carrier family 6 member 3 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | SLC6A3 | solute carrier family 6 member 3 [Source:HGNC Symbol;Acc:HGNC:11049] | 9258 | OMA, EggNOG |
Protein Classes
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Monoamine transporter subfamily / Sodium-dependent dopamine transporter
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Monoamine transporter subfamily / Sodium-dependent dopamine transporter
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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