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| Description | Tyrosine-protein kinase JAK3 |
|---|
Gene and Protein Information
| Gene ID | 3718 |
|---|---|
| Uniprot Accession IDs | P52333 Q13259 Q13260 Q13611 Q8N1E8 Q99699 Q9Y6S2 |
| Ensembl ID | ENSG00000105639 |
| Symbol | JAKL LJAK JAK-3 L-JAK JAK3_HUMAN |
| Chromosome | 19 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
| Sequence |
MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTAHPEGKHHSLSFS
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 748892 | JAK3 | Janus kinase 3 | 9598 | VGNC:11234 | OMA, EggNOG |
| Macaque | 720040 | JAK3 | Janus kinase 3 | 9544 | OMA, EggNOG | |
| Mouse | 16453 | Jak3 | Janus kinase 3 | 10090 | MGI:99928 | Inparanoid, OMA, EggNOG |
| Rat | 25326 | Jak3 | Janus kinase 3 | 10116 | RGD:2940 | Inparanoid, OMA, EggNOG |
| Dog | 610004 | JAK3 | Janus kinase 3 | 9615 | VGNC:42177 | Inparanoid, OMA, EggNOG |
| Horse | 100147451 | JAK3 | Janus kinase 3 | 9796 | VGNC:19214 | Inparanoid, OMA, EggNOG |
| Cow | 538276 | JAK3 | Janus kinase 3 | 9913 | VGNC:30366 | Inparanoid, OMA, EggNOG |
| Pig | 100518649 | JAK3 | Janus kinase 3 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100010720 | JAK3 | Janus kinase 3 | 13616 | Inparanoid, OMA | |
| Xenopus | 100135373 | jak3 | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 8364 | XB-GENE-5904698 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / JAKA family / Tyrosine-protein kinase jak3
protein / Kinase / Protein kinase / TK group / JAKA family / Tyrosine-protein kinase jak3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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