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| Description | Insulin-like growth factor 1 receptor |
|---|
Gene and Protein Information
| Gene ID | 3480 |
|---|---|
| Uniprot Accession IDs | P08069 B1B5Y2 Q14CV2 Q9UCC0 |
| Ensembl ID | ENSG00000140443 |
| Symbol | IGFR CD221 IGFIR JTK13 |
| Chromosome | 15 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. |
| Sequence |
MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 453676 | IGF1R | insulin like growth factor 1 receptor | 9598 | VGNC:11907 | OMA, EggNOG |
| Macaque | 708227 | IGF1R | insulin like growth factor 1 receptor | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 16001 | Igf1r | insulin-like growth factor I receptor | 10090 | MGI:96433 | Inparanoid, OMA, EggNOG |
| Rat | 25718 | Igf1r | insulin-like growth factor 1 receptor | 10116 | RGD:2869 | Inparanoid, OMA, EggNOG |
| Dog | 442951 | IGF1R | insulin like growth factor 1 receptor | 9615 | VGNC:41896 | Inparanoid, OMA |
| Horse | 100055698 | IGF1R | insulin like growth factor 1 receptor | 9796 | VGNC:18968 | Inparanoid, OMA |
| Anole lizard | 100554064 | igf1r | insulin like growth factor 1 receptor | 28377 | Inparanoid, OMA | |
| Xenopus | 100329112 | igf1r | insulin like growth factor 1 receptor | 8364 | XB-GENE-484032 | Inparanoid, OMA |
| Zebrafish | 245702 | igf1rb | insulin-like growth factor 1b receptor | 7955 | ZDB-GENE-020503-2 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / INSR family / Insulin-like growth factor 1 receptor
protein / Kinase / Protein kinase / TK group / INSR family / Insulin-like growth factor 1 receptor
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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