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IRAK4

Description Interleukin-1 receptor-associated kinase 4

Gene and Protein Information

Gene ID 51135
Uniprot Accession IDs Q9NWZ3 Q69FE1 Q8TDF7 Q9Y589 IRAK-4
Ensembl ID ENSG00000198001
Symbol IPD1 REN64 IRAK-4 NY-REN-64
Chromosome 12
Family Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Sequence
MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 466962 IRAK4 interleukin 1 receptor associated kinase 4 9598 VGNC:5434 OMA, EggNOG
Macaque 700568 IRAK4 interleukin 1 receptor associated kinase 4 9544 Inparanoid, OMA, EggNOG
Mouse 266632 Irak4 interleukin-1 receptor-associated kinase 4 10090 MGI:2182474 Inparanoid, OMA, EggNOG
Rat 300177 Irak4 interleukin-1 receptor-associated kinase 4 10116 RGD:1305303 Inparanoid, OMA, EggNOG
Dog 486601 IRAK4 interleukin 1 receptor associated kinase 4 9615 VGNC:42089 Inparanoid, OMA, EggNOG
Horse 100054848 IRAK4 interleukin 1 receptor associated kinase 4 9796 VGNC:19128 Inparanoid, OMA, EggNOG
Cow 533692 IRAK4 interleukin 1 receptor associated kinase 4 9913 VGNC:30268 Inparanoid, OMA, EggNOG
Pig 100127166 IRAK4 interleukin 1 receptor associated kinase 4 9823 Inparanoid, OMA, EggNOG
Opossum 100019202 IRAK4 interleukin 1 receptor associated kinase 4 13616 Inparanoid, OMA, EggNOG
Chicken 417796 IRAK4 interleukin 1 receptor associated kinase 4 9031 CGNC:7297 Inparanoid, OMA, EggNOG
Anole lizard 100556834 irak4 interleukin 1 receptor associated kinase 4 28377 Inparanoid, OMA, EggNOG
Xenopus 733738 irak4 interleukin 1 receptor associated kinase 4 8364 XB-GENE-492219 Inparanoid, OMA, EggNOG
Zebrafish 393132 irak4 interleukin-1 receptor-associated kinase 4 7955 ZDB-GENE-040426-738 Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    IRAK family    /    Interleukin-1 receptor-associated kinase 4

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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