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Targets(Human)
KDR

KDR

Description	Vascular endothelial growth factor receptor 2

Gene and Protein Information

Gene ID	3791
Uniprot Accession IDs	P35968 A2RRS0 B5A925 C5IFA0 O60723 Q14178 VEGFR-2
Ensembl ID	ENSG00000128052
Symbol	FLK1 VEGFR2 FLK1 CD309 VEGFR VEGFR2
Chromosome	4
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence	MQSKVLLAVALWLCVETRAASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVISFHVTRGPEITLQPDMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVGTAVIAMFFWLLLVIILRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSGMVLASEELKTLEDRTKLSPSFGGMVPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSEEAELLKLIEIGVQTGSTAQILQPDSGTTLSSPPV Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	461315	KDR	kinase insert domain receptor	9598	VGNC:755	OMA, EggNOG
Macaque	698293	KDR	kinase insert domain receptor	9544		Inparanoid, OMA, EggNOG
Mouse	16542	Kdr	kinase insert domain protein receptor	10090	MGI:96683	Inparanoid, OMA, EggNOG
Rat	25589	Kdr	kinase insert domain receptor	10116	RGD:2965	Inparanoid, OMA
Dog	482154	KDR	kinase insert domain receptor	9615	VGNC:42331	Inparanoid, OMA, EggNOG
Horse	100033959	KDR	kinase insert domain receptor	9796	VGNC:19344	Inparanoid, OMA, EggNOG
Cow	407170	KDR	kinase insert domain receptor	9913	VGNC:30535	Inparanoid, OMA, EggNOG
Pig	397311	KDR	kinase insert domain receptor	9823		Inparanoid, OMA, EggNOG
Opossum	100017311	KDR	kinase insert domain receptor	13616		Inparanoid, OMA, EggNOG
Platypus		KDR	kinase insert domain receptor [Source:HGNC Symbol;Acc:HGNC:6307]	9258		OMA, EggNOG
Chicken	395323	KDR	kinase insert domain receptor	9031	CGNC:10404	Inparanoid, OMA
Anole lizard	100551738	kdr	kinase insert domain receptor	28377		Inparanoid, OMA
Xenopus	100487501	kdr	kinase insert domain receptor	8364	XB-GENE-6053213	Inparanoid, OMA
Zebrafish	554230	kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	7955	ZDB-GENE-041001-112	Inparanoid, OMA

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / TK group / VEGFR family / Vascular endothelial growth factor receptor 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

🔙[Back to Target (Human)]

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