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Targets(Human)
GABRA1

GABRA1

Description	Gamma-aminobutyric acid receptor subunit alpha-1

Gene and Protein Information

Gene ID	2554
Uniprot Accession IDs	P14867 D3DQK6 Q8N629
Ensembl ID	ENSG00000022355
Symbol	EJM ECA4 EJM5 EIEE19
Chromosome	5
Family	Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
Sequence	MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	462241	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9598	VGNC:8618	OMA, EggNOG
Macaque	574302	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9544		Inparanoid, OMA, EggNOG
Mouse	14394	Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	10090	MGI:95613	Inparanoid, OMA, EggNOG
Rat	29705	Gabra1	gamma-aminobutyric acid type A receptor alpha1 subunit	10116	RGD:61855	Inparanoid, OMA, EggNOG
Dog	489143	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9615	VGNC:41053	Inparanoid, OMA, EggNOG
Horse	100070870	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9796	VGNC:18191	Inparanoid, OMA, EggNOG
Cow	780973	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9913	VGNC:29191	Inparanoid, OMA, EggNOG
Pig	100516706	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9823		OMA, EggNOG
Opossum	100030540	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	13616		Inparanoid, EggNOG
Chicken	374214	GABRA1	gamma-aminobutyric acid type A receptor alpha1 subunit	9031	CGNC:49087	Inparanoid, OMA
Anole lizard	100556680	gabra1	gamma-aminobutyric acid type A receptor alpha1 subunit	28377		Inparanoid, OMA
Zebrafish	768183	gabra1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	7955	ZDB-GENE-061013-194	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ligand-gated ion channel    /    Gamma-aminobutyric acid receptor subunit alpha-1
protein    /    transporter    /    ion channel    /    Gamma-aminobutyric acid receptor subunit alpha-1
protein    /    transporter    /    acetylcholine receptor    /    Gamma-aminobutyric acid receptor subunit alpha-1
protein    /    transporter    /    GABA receptor    /    Gamma-aminobutyric acid receptor subunit alpha-1
protein    /    transporter    /    receptor    /    Gamma-aminobutyric acid receptor subunit alpha-1

DTO Classes
protein / Ion channel / Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family / Gamma-aminobutyric acid receptor subfamily / GABRA1 sub-subfamily / Gamma-aminobutyric acid receptor subunit alpha-1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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