Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
S275436-1mg
|
1mg |
3
|
$84.90
|
|
|
S275436-5mg
|
5mg |
3
|
$338.90
|
|
|
S275436-10mg
|
10mg |
3
|
$541.90
|
|
|
S275436-25mg
|
25mg |
3
|
$948.90
|
|
|
S275436-50mg
|
50mg |
2
|
$1,517.90
|
|
Potent melanocortin 3 and 4 (MC 3 and MC 4 ) receptor antagonist
| Synonyms | SHU 9119 |
|---|---|
| Specifications & Purity | Moligand™, ≥95% |
| Biochemical and Physiological Mechanisms | Potent melanocortin 3 and 4 (MC 3 and MC 4 ) receptor antagonist (IC 50 values are 0.23 and 0.06 nM, respectively). Also shows MC 5 partial agonist activity (EC 50 = 0.12 nM). Dose-dependently increases food intake following central administration. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Action Type | AGONIST, ANTAGONIST |
| Mechanism of action | Agonist of MC 1 receptor;Antagonist of MC 3 receptor;Antagonist of MC 4 receptor;Agonist of MC 5 receptor |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Molecular Weight | 1074.25(free base) |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 17, 2025 | S275436 | |
| Certificate of Analysis | Jun 17, 2025 | S275436 | |
| Certificate of Analysis | Jun 17, 2025 | S275436 | |
| Certificate of Analysis | Jun 17, 2025 | S275436 | |
| Certificate of Analysis | Jun 17, 2025 | S275436 | |
| Certificate of Analysis | Jan 15, 2025 | S275436 | |
| Certificate of Analysis | Jan 15, 2025 | S275436 | |
| Certificate of Analysis | Jan 15, 2025 | S275436 | |
| Certificate of Analysis | Jan 15, 2025 | S275436 | |
| Certificate of Analysis | Jan 15, 2025 | S275436 |
| Solubility | Soluble in water |
|---|