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Rovalpituzumab (anti-DLL3) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to DLL3, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170576
Grouped product items
SKU Size
Availability
Price Qty
Ab170576-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170576-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$207.90
Ab170576-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$567.90
Ab170576-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$867.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Rovalpituzumab (anti-DLL3) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to DLL3, >95%, high purity, Human IgG1
Synonyms Delta3 | Drosophila Delta homolog 3
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity DLL3
Application ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Rovalpituzumab (anti-DLL3) is a humanized monoclonal antibody against delta-like protein 3 (DLL3). Rovalpituzumab (anti-DLL3) can be used in the synthesis of antibody-drug conjugate (ADC), Rovalpituzumab Tesirine. Rovalpituzumab (anti-DLL3) has activity against small cell lung cancer (SCLC).

Purity:

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.5 kDa (Light Chain) & 50.9 kDa (Heavy Chain), under reducing conditions; 174.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1613313-01-1

Associated Targets(Human)

DLL3 Tbio Delta-like protein 3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Rovalpituzumab (anti-DLL3) (Ab170576) - SEC
The purity of Rovalpituzumab (anti-DLL3) (Ab170576) is more than 95% verified by HPLC.

Rovalpituzumab (anti-DLL3) (Ab170576) - ELISA
Immobilized human-DLL3-ECD-His at 2 μg/mL can bind Rovalpituzumab (anti-DLL3) (Ab170576) with the EC₅₀ of 21.71 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0900995 Certificate of Analysis Sep 11, 2023 Ab170576
ZJ23F0900994 Certificate of Analysis Sep 11, 2023 Ab170576

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