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Recombinant p21 Antibody - Primary antibody, specific to p21, Mouse IgG2a

COA COA
    Application:
  • IHC
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG2a
  • Clone Number: MyM1-p21
  • Conjugation: Unconjugated
In stock
Item Number
Ab119617
Grouped product items
SKU Size
Availability
 Price Qty
Ab119617-10μl
10μl
5
$49.90
Ab119617-50μl
50μl
2
$159.90
Ab119617-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$259.90
Ab119617-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant (MyM1-p21); Mouse anti Human p21 Antibody; IHC; Unconjugated

View related series
Click to view target information: CDKN1A
Accession#:P38936 (4) CDKN1A (4) Gene ID:1026 (4) p21 (4)

Basic Description

Product Name Recombinant p21 Antibody - Primary antibody, specific to p21, Mouse IgG2a
Synonyms CAP20 antibody | CDK-interacting protein 1 antibody | CDKI antibody | CDKN1 antibody | Cdkn1a antibody | CDN1A_HUMAN antibody | CIP1 antibody | Cyclin Dependent Kinase Inhibitor 1A antibody | Cyclin-dependent kinase inhibitor 1 antibody | Cyclin-dependent
Specifications & Purity ExactAb™, Validated, Recombinant, 2.4 mg/mL
Host species Mouse
Specificity p21
Positive Control IHC: Human tonsil and breast cancer tissues.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Mouse anti Human p21 Antibody, Recombinant (MyM1-p21), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Product Properties

Isotype Mouse IgG2a
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 2.4 mg/mL
Storage Temp Store at 2-8°C,Avoid repeated freezing and thawing
Shipped In Wet ice
Stability And Storage Store at 2-8°C long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CDKN1A Tchem Cyclin-dependent kinase inhibitor 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CDKN1A Tchem CDK-interacting protein 1 (92 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant p21 Antibody (Ab119617) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Recombinant p21 Antibody (Ab119617) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue labelling p21 with Recombinant p21 Antibody (Ab119617) at 1/100 dilution. The section was incubated with Ab119617 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Application

Application Dilution info
IHC

1/100 - 1/200

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0404783 Certificate of Analysis Apr 23, 2024 Ab119617
ZJ24F0404782 Certificate of Analysis Apr 23, 2024 Ab119617

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