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Recombinant Langerin Antibody - Primary antibody, specific to Langerin, Mouse IgG2b

    Application:
  • IHC
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG2b
  • Clone Number: MyM1-CD207
  • Conjugation: Unconjugated
In stock
Item Number
Ab112770
Grouped product items
SKU Size
Availability
Price Qty
Ab112770-10μl
10μl
5
$49.90
Ab112770-50μl
50μl
2
$139.90
Ab112770-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$209.90
Ab112770-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90

Recombinant (MyM1-CD207); Mouse anti Human Langerin Antibody; IHC; Unconjugated

Basic Description

Product Name Recombinant Langerin Antibody - Primary antibody, specific to Langerin, Mouse IgG2b
Synonyms C type lectin domain family 4 member K antibody | C-type lectin domain family 4 member K antibody | CD 207 antibody | CD207 antibody | CD207 antigen antibody | CD207 antigen, langerin antibody | CD207 molecule antibody | CLC4K_HUMAN antibody | CLEC 4K ant
Specifications & Purity ExactAb™, Validated, Recombinant, 0.12 mg/mL
Host species Mouse
Specificity Langerin
Positive Control IHC: Human skin tissue.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Mouse anti Human Langerin Antibody, Recombinant (MyM1-CD207), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Product Properties

Isotype Mouse IgG2b
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.12 mg/mL
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Store at 2-8°C long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CD207 Tbio C-type lectin domain family 4 member K (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant Langerin Antibody (Ab112770) - IHC
Immunohistochemistry analysis of paraffin-embedded human skin tissue labelling Langerin with Recombinant Langerin Antibody (Ab112770) at 1/100 dilution. The section was incubated with Ab112770 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Application

Application Dilution info
IHC

1/100 - 1/200

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0505262 Certificate of Analysis May 09, 2024 Ab112770
ZJ24F0505261 Certificate of Analysis May 09, 2024 Ab112770

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