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Ranibizumab (anti-VEGFA) - Primary antibody, specific to VEGFA, >95%, high purity, Human IgG1-CH1, INHIBITOR of Vascular endothelial growth factor A inhibitor, INHIBITOR of Vascular endothelial growth factor A inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Rabbit
  • Isotype: Human IgG1-CH1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176067
Grouped product items
SKU Size
Availability
Price Qty
Ab176067-100μg
100μg
10
$149.90
Ab176067-1mg
1mg
4
$719.90
Ab176067-5mg
5mg
1
$1,799.90
Ab176067-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,879.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1-CH1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Ranibizumab (anti-VEGFA) - Primary antibody, specific to VEGFA, >95%, high purity, Human IgG1-CH1, INHIBITOR of Vascular endothelial growth factor A inhibitor
Synonyms Folliculostellate cell-derived growth factor antibody | Glioma-derived endothelial cell mitogen antibody | MGC70609 antibody | MVCD1 antibody | Vascular endothelial growth factor A antibody | vascular endothelial growth factor A121 antibody | vascular end
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity VEGFA
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Vascular endothelial growth factor A inhibitor
Product Description

Ranibizumab (anti-VEGFA) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165). Ranibizumab (anti-VEGFA) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1-CH1
Light Chain Type kappa
SDS-PAGE 49.19 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 347396-82-1

Associated Targets(Human)

VEGFA Tclin Vascular endothelial growth factor A (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Ranibizumab (anti-VEGFA) (Ab176067) - ELISA
Immobilized Recombinant Human VEGF Protein (rp155965) at 1 μg/mL can bind Ranibizumab (anti-VEGFA) (Ab176067) with the EC₅₀ of 134.4 ng/mL.

Ranibizumab (anti-VEGFA) (Ab176067) - SEC
The purity of Ranibizumab (anti-VEGFA) (Ab176067) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303078 Certificate of Analysis Mar 08, 2024 Ab176067
ZJ24F0303077 Certificate of Analysis Mar 08, 2024 Ab176067
ZJ24F0303076 Certificate of Analysis Mar 08, 2024 Ab176067

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