Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176067-100μg
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100μg |
10
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$149.90
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Ab176067-1mg
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1mg |
4
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$719.90
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Ab176067-5mg
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5mg |
1
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$1,799.90
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Ab176067-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,879.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1-CH1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Ranibizumab (anti-VEGFA) - Primary antibody, specific to VEGFA, >95%, high purity, Human IgG1-CH1, INHIBITOR of Vascular endothelial growth factor A inhibitor |
|---|---|
| Synonyms | Folliculostellate cell-derived growth factor antibody | Glioma-derived endothelial cell mitogen antibody | MGC70609 antibody | MVCD1 antibody | Vascular endothelial growth factor A antibody | vascular endothelial growth factor A121 antibody | vascular end |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | VEGFA |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Vascular endothelial growth factor A inhibitor |
| Product Description |
Ranibizumab (anti-VEGFA) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165). Ranibizumab (anti-VEGFA) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research. |
| Isotype | Human IgG1-CH1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 49.19 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 347396-82-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Ranibizumab (anti-VEGFA) (Ab176067) - ELISA
Immobilized Recombinant Human VEGF Protein (rp155965) at 1 μg/mL can bind Ranibizumab (anti-VEGFA) (Ab176067) with the EC₅₀ of 134.4 ng/mL.
Ranibizumab (anti-VEGFA) (Ab176067) - SEC
The purity of Ranibizumab (anti-VEGFA) (Ab176067) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 08, 2024 | Ab176067 | |
| Certificate of Analysis | Mar 08, 2024 | Ab176067 | |
| Certificate of Analysis | Mar 08, 2024 | Ab176067 |
Starting at $66.90
Starting at $66.90
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Starting at $66.90