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Brolucizumab (anti-VEGFA) - Primary antibody, specific to VEGFA, Human IgG1-CS

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1-CS
  • Conjugation: Unconjugated
In stock
Item Number
Ab191965
Grouped product items
SKU Size
Availability
Price Qty
Ab191965-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab191965-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab191965-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$739.90
Ab191965-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgGIgG1-CS; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Brolucizumab (anti-VEGFA) - Primary antibody, specific to VEGFA, Human IgG1-CS
Synonyms Folliculostellate cell-derived growth factor antibody | Glioma-derived endothelial cell mitogen antibody | MGC70609 antibody | MVCD1 antibody | Vascular endothelial growth factor A antibody | vascular endothelial growth factor A121 antibody | vascular end
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 re
Host species Human
Specificity VEGFA
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Brolucizumab (anti-VEGFA) is a single-chain anti-VEGF-A antibody fragment. Brolucizumab (anti-VEGFA) can be used for the research of cancer.

Product Properties

Isotype Human IgG1-CS
SDS-PAGE 52.04 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1531589-13-5

Associated Targets(Human)

VEGFA Tclin Vascular endothelial growth factor A (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Brolucizumab (anti-VEGFA) (Ab191965) - ELISA
Immobilized Recombinant Human VEGF protein (rp155965) at 1.0 μg/mL can bind Brolucizumab (anti-VEGFA) (Ab191965) with the EC₅₀ of 86.34 ng/mL.

Brolucizumab (anti-VEGFA) (Ab191965) - SEC
The purity of Brolucizumab (anti-VEGFA) (Ab191965) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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