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Applications
Transmembrane Transporters
Procyclidine Hydrochloride - 10mM in DMSO, high purity , Muscarinic acetylcholine receptor M1 antagonist, CAS No.1508-76-5(DMSO), Muscarinic acetylcholine receptor M1 antagonist
Procyclidine Hydrochloride - 10mM in DMSO, high purity , Muscarinic acetylcholine receptor M1 antagonist, CAS No.1508-76-5(DMSO), Muscarinic acetylcholine receptor M1 antagonist
Basic Description
Synonyms
Procyclidine hydrochloride | 1508-76-5 | Procyclidine HCl | Kemadrin | Tricyclamol hydrochloride | Procyclidine (hydrochloride) | (+-)-Procyclidine hydrochloride | UNII-CQC932Z7YW | alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol hydrochloride | EINECS 216-141-8 | CQC932
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Procyclidine is a synthetic anti-cholinergic agent and atropine-like antispasmodic. It exhibits therapeutic effects against Parkinson′s disease and schizophrenia. Procyclidine acts as a muscarinic receptor antagonist. It also affects N-methyl-D-aspartate
Storage Temp
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Mechanism of action
Muscarinic acetylcholine receptor M1 antagonist
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organic nitrogen compounds
Class
Organonitrogen compounds
Subclass
Amines
Intermediate Tree Nodes
Not available
Direct Parent
Aralkylamines
Alternative Parents
N-alkylpyrrolidines Benzene and substituted derivatives Tertiary alcohols 1,3-aminoalcohols Trialkylamines Azacyclic compounds Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives Aromatic alcohols
Molecular Framework
Aromatic heteromonocyclic compounds
Substituents
Aralkylamine - Monocyclic benzene moiety - Benzenoid - N-alkylpyrrolidine - 1,3-aminoalcohol - Pyrrolidine - Tertiary alcohol - Tertiary amine - Tertiary aliphatic amine - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Aromatic alcohol - Hydrochloride - Hydrocarbon derivative - Organooxygen compound - Organopnictogen compound - Alcohol - Aromatic heteromonocyclic compound
Description
This compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
External Descriptors
hydrochloride
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride
INCHI
InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H
InChIKey
ZFSPFXJSEHCTTR-UHFFFAOYSA-N
Smiles
C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
Isomeric SMILES
C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
WGK Germany
3
RTECS
UY1926000
PubChem CID
207841
Molecular Weight
323.9
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Sensitivity
Moisture sensitive.
Molecular Weight
323.900 g/mol
XLogP3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
5
Exact Mass
323.202 Da
Monoisotopic Mass
323.202 Da
Topological Polar Surface Area
23.500 Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
301.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
2
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