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Procyclidine Hydrochloride - 10mM in DMSO, high purity , Muscarinic acetylcholine receptor M1 antagonist, CAS No.1508-76-5(DMSO), Muscarinic acetylcholine receptor M1 antagonist

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
P580496
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P580496-1ml
1ml
Available within 8-12 weeks(?)
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$256.90
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Compound libraries (12325)

Basic Description

Synonyms Procyclidine hydrochloride | 1508-76-5 | Procyclidine HCl | Kemadrin | Tricyclamol hydrochloride | Procyclidine (hydrochloride) | (+-)-Procyclidine hydrochloride | UNII-CQC932Z7YW | alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol hydrochloride | EINECS 216-141-8 | CQC932
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Procyclidine is a synthetic anti-cholinergic agent and atropine-like antispasmodic. It exhibits therapeutic effects against Parkinson′s disease and schizophrenia. Procyclidine acts as a muscarinic receptor antagonist. It also affects N-methyl-D-aspartate
Storage Temp Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type ANTAGONIST
Mechanism of action Muscarinic acetylcholine receptor M1 antagonist

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic nitrogen compounds
Class Organonitrogen compounds
Subclass Amines
Intermediate Tree Nodes Not available
Direct Parent Aralkylamines
Alternative Parents N-alkylpyrrolidines  Benzene and substituted derivatives  Tertiary alcohols  1,3-aminoalcohols  Trialkylamines  Azacyclic compounds  Organopnictogen compounds  Hydrochlorides  Hydrocarbon derivatives  Aromatic alcohols  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Aralkylamine - Monocyclic benzene moiety - Benzenoid - N-alkylpyrrolidine - 1,3-aminoalcohol - Pyrrolidine - Tertiary alcohol - Tertiary amine - Tertiary aliphatic amine - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Aromatic alcohol - Hydrochloride - Hydrocarbon derivative - Organooxygen compound - Organopnictogen compound - Alcohol - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
External Descriptors hydrochloride

Associated Targets(Human)

HEK293 (82097 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol;hydrochloride
INCHI InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H
InChIKey ZFSPFXJSEHCTTR-UHFFFAOYSA-N
Smiles C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
Isomeric SMILES C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O.Cl
WGK Germany 3
RTECS UY1926000
PubChem CID 207841
Molecular Weight 323.9

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity Moisture sensitive.
Molecular Weight 323.900 g/mol
XLogP3
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 5
Exact Mass 323.202 Da
Monoisotopic Mass 323.202 Da
Topological Polar Surface Area 23.500 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 301.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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