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Recombinant Human GDNF GMP ProteinSpecies: Human Accession #: P39905-1Expression system: HEK293 Protein Tag: No tag Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera. The specific activity of recombinant human GDNF is >5.0 x 10^5 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.Synonyms: Glial Cell line-derived Growth Factor | Astrocyte-derived trophic factor | ATF | ATF1 | ATF2 | GDNF | glial cell deri...
