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PharmPure™ GMP Portfolio

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  1. Recombinant Human EGF Protein
    Cas Number: 62253-63-8        Compound CID:  16143379
    Formula:  C270H401N73O83S7        Molecular Weight: 6.5kD
      Species: Human    Accession #: P01133    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <1.0 EU/mg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.    
    IUPAC Name:  (4S)-5-[[(2S)-1-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-4-carbamimidshow more
    SMILES:  CCC(C)C(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(Cshow more
    InChIKey: GVUGOAYIVIDWIO-UFWWTJHBSA-N
    InChI:  InChI=1S/C270H401N73O83S7/c1-24-134(19)217(262(420)293-112-201(355)298-161(69-74-205(359)360)229(387)301-160(45-35-82-286-269(279)280)228(386)333-192(show more
    Synonyms: UNII-TZK30RF92W | Human EGF | MG 111 | CCRIS 6735 | Nepidermin [INN] | NEPIDERMIN | Human epidermal growth factor | T...
  2. Recombinant Human LR3 IGF-I/IGF-1 GMP Protein
      Species: Human    Accession #: P05019.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a serum-free cell proliferation assay using MCF7 human breast cancer cells. The ED50 for this effect is 0.3-1.5 ng/mL. IGFBP-3 does not inhibit its activity.    
    Synonyms: IBP1 | IGF1 | IGF-1 | IGF1A | IGFI | IGF-I | IGF-IA | IGF-IB | insulin-like growth factor 1 (somatomedin C) | insulin...
  3. Recombinant Human HGF GMP Protein
      Species: Human    Accession #: P14210-1    
      Expression system: HEK293    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF WHO International Standard (NIBSC code: 96/564).    
    Synonyms: Hepatocyte Growth Factor | deafness, autosomal recessive 39 | DFNB39 | EC 3.4.21 | EC 3.4.21.7 | fibroblast-derived t...
  4. Recombinant Human IL-21 GMP Protein
      Species: Human    Accession #: Q9HBE4    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using B9 mouse hybridoma cells. The ED50 for this effect is 5.00-50.0 ng/mL. The specific activity of recombinant human IL-21 is >1.00 x 10^6 units/mg, which is calibrated against an internal reference standard for human IL-21.    
    Synonyms: Interleukin 21 | CVID11 | IL21 | IL-21 | interleukin-21 | interleukin-21 isoform | Za11
  5. Recombinant Human Thrombopoietin GMP Protein
      Species: Human    Accession #: NP_000451.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).    
    Synonyms: Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating fac...
  6. Recombinant Human Sonic Hedgehog/Shh (C24II) GMP Protein
      Species: Human    Accession #: NP_000184.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.1-0.4 µg/mL.    
    Synonyms: HHG1 | HHG-1 | HLP3 | HPE3 | MCOPCB5 | MCOPCB5sonic hedgehog (Drosophila) homolog | Shh | ShhNC | SMMCI | SMMCIsonic ...
  7. Recombinant Human BMP-2 GMP Protein
      Species: Human    Accession #: P12643    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 40-200 ng/mL. The specific activity of recombinant human BMP-2 is >5.0 x 10^5 units/mg, which is calibrated against the human BMP-2 WHO Standard (NIBSC code: 93/574).    
    Synonyms: Bone Morphogenetic Protein 2 | BDA2 | BMP2 | BMP-2 | BMP-2A | BMP2A | Bone morphogenetic protein 2A | SSFSC | SSFSC1
  8. Recombinant Human Insulin Protein
    Cas Number: 11061-68-0
    Formula:  C257H383N65O77S6        Molecular Weight: 5807.57
      Species: Human    Accession #: P01308    
      Expression system: Yeast    Protein Tag: No tag     Endotoxin Concentration: <10 EU/mg    
      Bioactivity: ≥15 U/mg    
    IUPAC Name:  4-[[2-[[88-[[5-amino-2-[[2-[[2-[[2-[(2-aminoacetyl)amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amishow more
    SMILES:  CCC(C)C1C(=O)NC2CSSCC(C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(NC(=O)C(NC(=Oshow more
    InChIKey: PBGKTOXHQIOBKM-UHFFFAOYSA-N
    InChI:  InChI=1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(2show more
    Synonyms: ins | INS_HUMAN | Insulin A chain | Insulin B chain | Preproinsulin | Proinsulin | Proinsulin precursor | IDDM | ILPR...
  9. Recombinant Human Fibronectin Fragment Protein
    Cas Number: 86088-83-7        EC Number: 289-149-2
    Formula:        
      Species: Human    Accession #: P02751    
      Expression system: E. coli    Protein Tag: C-His    Endotoxin Concentration: <10 EU/mg    
      Bioactivity: It has the effect of promoting cell adhesion. Depending on the cell type, the optimal concentration is 0.2-1.5 μg/cm2    
    Synonyms: CIG | Cold-insoluble globulin | FN | ED-B | fibronectin 1 | Fibronectin | FINC | FN1 | FNZ | GFND | GFND2 | LETS | MS...
  10. Recombinant Human VEGF 165 Protein
      Species: Human    Accession #: P15692-4    
      Expression system: CHO    Protein Tag: C-His    Endotoxin Concentration: <10 EU/mg    
      Bioactivity: Measured in a cell proliferation assay using Human HUVEC cells. The ED50 for this effect is <2 ng/mL. The corresponding specific activity is>1×10^6 IU/mg.    
    Synonyms: Vascular Endothelial Growth Factor | MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability facto...
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