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PharmPure™ GMP Portfolio

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  1. Recombinant Mouse IL-4 Protein
      Species: Mouse    Accession #: P07750    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.    
    Synonyms: B cell growth factor 1 | BCDF | B-cell stimulatory factor 1 | BCGF1 | BCGF-1 | binetrakin | BSF1 | BSF-1 | IL4 | IL-4...
  2. Recombinant Human/Mouse/Rat GDF-8/Myostatin GMP Protein
      Species: Mouse    Accession #: O08689    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 2-10 ng/mL.    
    Synonyms: Growth Differentiation Factor 8 | GDF8 | GDF-8 | growth/differentiation factor 8 | MSLHP | MSTN | Myostatin | Cmpt | ...
  3. Recombinant Human BDNF GMP Protein
      Species: Human    Accession #: P23560-1    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <10 EU/mg    
      Bioactivity: The activity is determined by the dose-dependent proliferation of C6 cell sand is typically between 0.5-1.5 ug/mL. Corresponding to a specific Activity of 1 x 10^3 units/mg.    
    Synonyms: Abrineurin | BDNF | Abrineurin | ANON2 | BDNF | brain-derived neurotrophic factor | BULN2 | MGC34632 | Neurotrophin |...
  4. Recombinant Human/Mouse/Rat Activin A GMP Protein
      Species: Human    Accession #: P08476    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50for this effect is 0.2-1.2 ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard (NIBSC code: 91/626).    
    Synonyms: Activin A | activin AB alpha polypeptide | Activin beta-A chain | erythroid differentiation factor | Erythroid differ...
  5. Recombinant Human GDNF GMP Protein
      Species: Human    Accession #: P39905-1    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera. The specific activity of recombinant human GDNF is >5.0 x 10^5 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.    
    Synonyms: Glial Cell line-derived Growth Factor | Astrocyte-derived trophic factor | ATF | ATF1 | ATF2 | GDNF | glial cell deri...
  6. Recombinant Human HGF GMP Protein
      Species: Human    Accession #: P14210-1    
      Expression system: HEK293    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF WHO International Standard (NIBSC code: 96/564).    
    Synonyms: Hepatocyte Growth Factor | deafness, autosomal recessive 39 | DFNB39 | EC 3.4.21 | EC 3.4.21.7 | fibroblast-derived t...
  7. Recombinant Human Wnt-3a GMP Protein
      Species: Human    Accession #: NP_149122.1    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce Topflash reporterBioactivity in CHO-K1 cells. The ED50 for this effect is <30ng/ml.    
    Synonyms: MGC119418 | MGC119419 | MGC119420 | protein Wnt-3a | wingless-type MMTV integration site family, member 3A | Wnt3a | ...
  8. Recombinant Human Noggin GMP Protein
      Species: Human    Accession #: Q13253.1    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4    
    Synonyms: NOG | Noggin | SYM1 | symphalangism 1 (proximal) | synostoses (multiple) syndrome 1 | SYNS1 | SYNS1A
  9. Recombinant Human TGF-beta 1 GMP Protein
      Species: Human    Accession #: P01137.2    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/mL.The specific activity of recombinant human TGF-β1 GMP is >1.0 x 10^7 units/mg, which is calibrated against the human TGF‑β1 Standard (NIBSC code: 89/514).    
    Synonyms: CED | LAP | DPD1 | latency-associated peptide | TGF beta | TGF beta1 | TGFB | TGFB1 | TGF-beta 1 protein | TGFbeta 1 ...
  10. Recombinant Human BMP-2 GMP Protein
      Species: Human    Accession #: P12643    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 40-200 ng/mL. The specific activity of recombinant human BMP-2 is >5.0 x 10^5 units/mg, which is calibrated against the human BMP-2 WHO Standard (NIBSC code: 93/574).    
    Synonyms: Bone Morphogenetic Protein 2 | BDA2 | BMP2 | BMP-2 | BMP-2A | BMP2A | Bone morphogenetic protein 2A | SSFSC | SSFSC1
  11. Recombinant Human Apo-Transferrin Protein
      Species: Human    Accession #: P02787    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <10 EU/mg    
      Bioactivity: 1、Measured in a serum-free cell proliferation assay using MDCK canine kidney epithelial cells. The ED50 for this effect is ≤5 μg/mL. 2、Measured in a cell proliferation assay using K562 human chronic myelogenous leukemia erythroleukemic cells. The ED50 for this effect is typically 39.45 ng/mL.    
    Synonyms: Serotransferrin | Transferrin | Beta-1 metal-binding globulin | Siderophilin | TF | TFQTL1 | PRO1557 | PRO2086 | HEL-...
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