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PharmPure™ GMP Portfolio

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  1. Recombinant Kex2 Protease
    Cas Number: 99676-46-7
      Species: Baker's yeast    Accession #: P13134    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Specific Activity: ≥10U/mg pro. UNIT DEFINITION: Under the conditions of 25°C and pH 8.0, the amount of enzyme needed to catalyze the conversion of 1 μmol Boc-QR R-pNA into products per minute is one enzyme activity unit (U).    
    Synonyms: KEX 2 | Kex2p | Kexin | KEX2 | QDS1 | SRB1 | VMA45
  2. Recombinant Human EGF Protein
    Cas Number: 62253-63-8        Compound CID:  16143379
    Formula:  C270H401N73O83S7        Molecular Weight: 6.5kD
      Species: Human    Accession #: P01133    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <1.0 EU/mg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.    
    IUPAC Name:  (4S)-5-[[(2S)-1-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-4-carbamimidshow more
    SMILES:  CCC(C)C(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(Cshow more
    InChIKey: GVUGOAYIVIDWIO-UFWWTJHBSA-N
    InChI:  InChI=1S/C270H401N73O83S7/c1-24-134(19)217(262(420)293-112-201(355)298-161(69-74-205(359)360)229(387)301-160(45-35-82-286-269(279)280)228(386)333-192(show more
    Synonyms: UNII-TZK30RF92W | Human EGF | MG 111 | CCRIS 6735 | Nepidermin [INN] | NEPIDERMIN | Human epidermal growth factor | T...
  3. Recombinant Mouse IL-4 Protein
      Species: Mouse    Accession #: P07750    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.    
    Synonyms: B cell growth factor 1 | BCDF | B-cell stimulatory factor 1 | BCGF1 | BCGF-1 | binetrakin | BSF1 | BSF-1 | IL4 | IL-4...
  4. Recombinant Human EGF Protein
    Cas Number: 62253-63-8        Compound CID:  16143379
    Formula:  C270H401N73O83S7        Molecular Weight: 6.5kD
      Species: Human    Accession #: P01133    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.2 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <0.9 ng/mL.    
    IUPAC Name:  (4S)-5-[[(2S)-1-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-4-carbamimidshow more
    SMILES:  CCC(C)C(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(Cshow more
    InChIKey: GVUGOAYIVIDWIO-UFWWTJHBSA-N
    InChI:  InChI=1S/C270H401N73O83S7/c1-24-134(19)217(262(420)293-112-201(355)298-161(69-74-205(359)360)229(387)301-160(45-35-82-286-269(279)280)228(386)333-192(show more
    Synonyms: beta-urogastrone | EGF | epidermal growth factor (beta-urogastrone) | epidermal growth factor | hEGF | HOMG4 | pro-ep...
  5. Recombinant Human EGF Protein
    Cas Number: 62253-63-8        Compound CID:  16143379
    Formula:  C270H401N73O83S7        Molecular Weight: 6.5kD
      Species: Human    Accession #: P01133    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.    
    IUPAC Name:  (4S)-5-[[(2S)-1-[[(2R)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-4-carbamimidshow more
    SMILES:  CCC(C)C(C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CS)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(Cshow more
    InChIKey: GVUGOAYIVIDWIO-UFWWTJHBSA-N
    InChI:  InChI=1S/C270H401N73O83S7/c1-24-134(19)217(262(420)293-112-201(355)298-161(69-74-205(359)360)229(387)301-160(45-35-82-286-269(279)280)228(386)333-192(show more
    Synonyms: Recombinant Human Epidermal Growth Factor | rhEGF | beta-urogastrone | EGF | epidermal growth factor (beta-urogastron...
  6. Recombinant Human GDNF GMP Protein
      Species: Human    Accession #: P39905-1    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera. The specific activity of recombinant human GDNF is >5.0 x 10^5 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.    
    Synonyms: Glial Cell line-derived Growth Factor | Astrocyte-derived trophic factor | ATF | ATF1 | ATF2 | GDNF | glial cell deri...
  7. Recombinant Human HGF GMP Protein
      Species: Human    Accession #: P14210-1    
      Expression system: HEK293    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF WHO International Standard (NIBSC code: 96/564).    
    Synonyms: Hepatocyte Growth Factor | deafness, autosomal recessive 39 | DFNB39 | EC 3.4.21 | EC 3.4.21.7 | fibroblast-derived t...
  8. Recombinant Human Wnt-3a GMP Protein
      Species: Human    Accession #: NP_149122.1    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce Topflash reporterBioactivity in CHO-K1 cells. The ED50 for this effect is <30ng/ml.    
    Synonyms: MGC119418 | MGC119419 | MGC119420 | protein Wnt-3a | wingless-type MMTV integration site family, member 3A | Wnt3a | ...
  9. Recombinant Human Noggin GMP Protein
      Species: Human    Accession #: Q13253.1    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4    
    Synonyms: NOG | Noggin | SYM1 | symphalangism 1 (proximal) | synostoses (multiple) syndrome 1 | SYNS1 | SYNS1A
  10. Recombinant Human Serum Albumin Protein
    Cas Number: 70024-90-7
    Formula:         Molecular Weight: 66.5kD
      Species: Human    Accession #: P02768    
      Expression system: Pichia pastoris    Protein Tag: No tag     Endotoxin Concentration: <0.5 EU/ml    
    Synonyms: rHSA,HSA,ALB,Albumin | alb | ALBU_HUMAN | Albumin | Albumin (32 AA) | Albumin (AA 34) | Analbuminemia | Bisalbuminemi...
  11. Recombinant Human Fetuin B Protein
      Species: Human    Accession #: Q9UGM5    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLU). The IC50 value is ≤100nM.    
    Synonyms: FETUB | Fetuin B | fetuin beta | fetuin phosphoprotein | fetuin-B | Fetuin-like protein | 16G2 | Gugu | IRL685
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