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PharmPure™ GMP Portfolio

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  1. Recombinant Human GDNF GMP Protein
      Species: Human    Accession #: P39905-1    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera. The specific activity of recombinant human GDNF is >5.0 x 10^5 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.    
    Synonyms: Glial Cell line-derived Growth Factor | Astrocyte-derived trophic factor | ATF | ATF1 | ATF2 | GDNF | glial cell deri...
  2. Recombinant Human IL-21 GMP Protein
      Species: Human    Accession #: Q9HBE4    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using B9 mouse hybridoma cells. The ED50 for this effect is 5.00-50.0 ng/mL. The specific activity of recombinant human IL-21 is >1.00 x 10^6 units/mg, which is calibrated against an internal reference standard for human IL-21.    
    Synonyms: Interleukin 21 | CVID11 | IL21 | IL-21 | interleukin-21 | interleukin-21 isoform | Za11
  3. Recombinant Human Thrombopoietin GMP Protein
      Species: Human    Accession #: NP_000451.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).    
    Synonyms: Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating fac...
  4. Recombinant Human SCF GMP Protein
      Species: Human    Accession #: P21583.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 1.00-8.00 ng/mL. The specific activity of recombinant human SCF is >1.0 x 10^6 units/mg, which is calibrated against the human SCF reference standard    
    Synonyms: c-kit Ligand | DCUA | DFNA69 | DKFZp686F2250 | familial progressive hyperpigmentation 2 | FPH2 | FPHH | KIT ligand | ...
  5. Recombinant Human M-CSF GMP Protein
      Species: Human    Accession #: NP_757350.2    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.5-1.5 ng/mL.The specific activity of Recombinant Human M-CSF is >6.0 x 10^7 IU/mg, which is calibrated against the human M-CSF WHO International Standard (NIBSC code: 89/512).    
    Synonyms: colony stimulating factor 1 (macrophage) | CSF1 | CSF-1 | Lanimostim | macrophage colony stimulating factor | macroph...
  6. Recombinant Human Fetuin B Protein
      Species: Human    Accession #: Q9UGM5    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLU). The IC50 value is ≤100nM.    
    Synonyms: FETUB | Fetuin B | fetuin beta | fetuin phosphoprotein | fetuin-B | Fetuin-like protein | 16G2 | Gugu | IRL685
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