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PharmPure™ GMP Portfolio

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  1. Recombinant Mouse IL-4 Protein
      Species: Mouse    Accession #: P07750    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.    
    Synonyms: B cell growth factor 1 | BCDF | B-cell stimulatory factor 1 | BCGF1 | BCGF-1 | binetrakin | BSF1 | BSF-1 | IL4 | IL-4...
  2. Recombinant Human GDNF GMP Protein
      Species: Human    Accession #: P39905-1    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera. The specific activity of recombinant human GDNF is >5.0 x 10^5 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.    
    Synonyms: Glial Cell line-derived Growth Factor | Astrocyte-derived trophic factor | ATF | ATF1 | ATF2 | GDNF | glial cell deri...
  3. Recombinant Human HGF GMP Protein
      Species: Human    Accession #: P14210-1    
      Expression system: HEK293    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF WHO International Standard (NIBSC code: 96/564).    
    Synonyms: Hepatocyte Growth Factor | deafness, autosomal recessive 39 | DFNB39 | EC 3.4.21 | EC 3.4.21.7 | fibroblast-derived t...
  4. Recombinant Human Wnt-3a GMP Protein
      Species: Human    Accession #: NP_149122.1    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to induce Topflash reporterBioactivity in CHO-K1 cells. The ED50 for this effect is <30ng/ml.    
    Synonyms: MGC119418 | MGC119419 | MGC119420 | protein Wnt-3a | wingless-type MMTV integration site family, member 3A | Wnt3a | ...
  5. Recombinant Human Noggin GMP Protein
      Species: Human    Accession #: Q13253.1    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4    
    Synonyms: NOG | Noggin | SYM1 | symphalangism 1 (proximal) | synostoses (multiple) syndrome 1 | SYNS1 | SYNS1A
  6. Recombinant Human Insulin Protein
    Cas Number: 11061-68-0
    Formula:  C257H383N65O77S6        Molecular Weight: 5807.57
      Species: Human    Accession #: P01308    
      Expression system: Yeast    Protein Tag: No tag     Endotoxin Concentration: <10 EU/mg    
      Bioactivity: ≥15 U/mg    
    IUPAC Name:  4-[[2-[[88-[[5-amino-2-[[2-[[2-[[2-[(2-aminoacetyl)amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amishow more
    SMILES:  CCC(C)C1C(=O)NC2CSSCC(C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(NC(=O)C(NC(=Oshow more
    InChIKey: PBGKTOXHQIOBKM-UHFFFAOYSA-N
    InChI:  InChI=1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(2show more
    Synonyms: ins | INS_HUMAN | Insulin A chain | Insulin B chain | Preproinsulin | Proinsulin | Proinsulin precursor | IDDM | ILPR...
  7. Recombinant Human Fetuin B Protein
      Species: Human    Accession #: Q9UGM5    
      Expression system: HEK293    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLU). The IC50 value is ≤100nM.    
    Synonyms: FETUB | Fetuin B | fetuin beta | fetuin phosphoprotein | fetuin-B | Fetuin-like protein | 16G2 | Gugu | IRL685
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