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PharmPure™ GMP Portfolio

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  1. Recombinant Human VEGF 165 GMP Protein
      Species: Human    Accession #: NP_001165097.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 1.50-12.0 ng/mL. The specific activity of recombinant human VEGF165 is > 8.0 x 10^5 units/mg, which is calibrated against the human VEGF165 WHO standard (NIBSC code: 02/286).    
    Synonyms: MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VE...
  2. Recombinant Human TNF-alpha GMP Protein
      Species: Human    Accession #: P01375.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25-100 pg/mL. The specific activity of recombinant human TNF-α GMP is >4.3 x 10^7 IU/mg, which is calibrated against the human TNF-α WHO International Standard (NIBSC code: 12/154).    
    Synonyms: APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
  3. Recombinant Human TGF-beta 1 GMP Protein
      Species: Human    Accession #: P01137.2    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/mL.The specific activity of recombinant human TGF-β1 GMP is >1.0 x 10^7 units/mg, which is calibrated against the human TGF‑β1 Standard (NIBSC code: 89/514).    
    Synonyms: CED | LAP | DPD1 | latency-associated peptide | TGF beta | TGF beta1 | TGFB | TGFB1 | TGF-beta 1 protein | TGFbeta 1 ...
  4. Recombinant Human IL-10 GMP Protein
      Species: Human    Accession #: P22301    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. The ED50 for this effect is 0.0750-0.750 ng/mL. The specific activity of recombinant human IL-10 is >2.50 x 10^6 units/mg, which is calibrated against the human IL-10 WHO Reference Reagent (NIBSC code: 93/722).    
    Synonyms: Interleukin 10 | CSIF | MGC126450 | Cytokine synthesis inhibitory factor | GVHDS | IL10 | IL-10 | IL10A | MGC126451 |...
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