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PharmPure™ GMP Portfolio

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  1. Recombinant Human IL-7 GMP Protein
      Species: Human    Accession #: P13232.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.100-0.500 ng/mL.The specific activity of Recombinant Human IL-7 is >1.00 x 10^8 units/mg, which is calibrated against the human IL-7 reference standard (NIBSC code: 90/530).    
    Synonyms: IL7 | IL-7 | IL-7interleukin-7 | interleukin 7 | Lymphopoietin-1 | PBGF
  2. Recombinant Human KGF/FGF-7 GMP Protein
      Species: Human    Accession #: P21781.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using 4MBr5 rhesus monkey epithelial cells.The ED50 for this effect is 6-60 ng/mL. The specific activity of recombinant human KGF/FGF-7 is >8.16 x 10^5 units/mg, which is calibrated against the human KGF/FGF-7 WHO Standard (NIBSC code: 03/150).    
    Synonyms: FGF7 | FGF-7 | fibroblast growth factor 7HBGF-7 | HBGF7 | HBGF-7 | Heparin-binding growth factor 7 | keratinocyte gro...
  3. Recombinant Human IL-15 GMP Protein
      Species: Human    Accession #: P40933    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.300-2.60 ng/mL. The specific activity of recombinant human IL-15 is >2.00 x 10^8 units/mg, which is calibrated against the human IL-15 reference standard (NIBSC code: 95/554).    
    Synonyms: Interleukin 15 | IL15 | IL-15 | MGC9721 | interleukin-15
  4. Recombinant Human IL-2 GMP Protein
      Species: Human    Accession #: P60568    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.0300-0.250 ng/mL. The specific activity of recombinant human IL-2 is >5.00 x 10^6 IU/mg, which is calibrated against the human IL-2 WHO International Standard (NIBSC code: 86/500).    
    Synonyms: Interleukin 2 | Aldesleukin | IL2 | IL-2 | lymphokine | interleukin-2 | involved in regulation of T-cell clonal expan...
  5. Recombinant Human VEGF 165 GMP Protein
      Species: Human    Accession #: NP_001165097.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 1.50-12.0 ng/mL. The specific activity of recombinant human VEGF165 is > 8.0 x 10^5 units/mg, which is calibrated against the human VEGF165 WHO standard (NIBSC code: 02/286).    
    Synonyms: MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VE...
  6. Recombinant Human TNF-alpha GMP Protein
      Species: Human    Accession #: P01375.1    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25-100 pg/mL. The specific activity of recombinant human TNF-α GMP is >4.3 x 10^7 IU/mg, which is calibrated against the human TNF-α WHO International Standard (NIBSC code: 12/154).    
    Synonyms: APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
  7. Recombinant Human TGF-beta 1 GMP Protein
      Species: Human    Accession #: P01137.2    
      Expression system: CHO    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/mL.The specific activity of recombinant human TGF-β1 GMP is >1.0 x 10^7 units/mg, which is calibrated against the human TGF‑β1 Standard (NIBSC code: 89/514).    
    Synonyms: CED | LAP | DPD1 | latency-associated peptide | TGF beta | TGF beta1 | TGFB | TGFB1 | TGF-beta 1 protein | TGFbeta 1 ...
  8. Recombinant Human Betacellulin GMP Protein
      Species: Human    Accession #: P35070    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.100-1.50 ng/mL.    
    Synonyms: Betacellulin | BTC | probetacellulin
  9. Recombinant Human IL-10 GMP Protein
      Species: Human    Accession #: P22301    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. The ED50 for this effect is 0.0750-0.750 ng/mL. The specific activity of recombinant human IL-10 is >2.50 x 10^6 units/mg, which is calibrated against the human IL-10 WHO Reference Reagent (NIBSC code: 93/722).    
    Synonyms: Interleukin 10 | CSIF | MGC126450 | Cytokine synthesis inhibitory factor | GVHDS | IL10 | IL-10 | IL10A | MGC126451 |...
  10. Recombinant Human M-CSF GMP Protein
      Species: Human    Accession #: NP_757350.2    
      Expression system: E. coli    Protein Tag: No tag     Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 0.5-1.5 ng/mL.The specific activity of Recombinant Human M-CSF is >6.0 x 10^7 IU/mg, which is calibrated against the human M-CSF WHO International Standard (NIBSC code: 89/512).    
    Synonyms: colony stimulating factor 1 (macrophage) | CSF1 | CSF-1 | Lanimostim | macrophage colony stimulating factor | macroph...
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