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PharmPure™ GMP Portfolio
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Recombinant Human IL-6 GMP ProteinSpecies: Human Accession #: P05231.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. The ED50 for this effect is 0.2‑0.8 ng/mL. The specific activity of Recombinant Human IL-6 is >1.0 x 10^8 IU/mg, which is calibrated against the human IL‑6 WHO International Standard(NIBSC code: 89/548).Synonyms: B-cell differentiation factor | B-cell stimulatory factor 2 | BSF2 | BSF-2 | CDF | CTL differentiation factor | HSF |...
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Recombinant Human IL-7 GMP ProteinSpecies: Human Accession #: P13232.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.100-0.500 ng/mL.The specific activity of Recombinant Human IL-7 is >1.00 x 10^8 units/mg, which is calibrated against the human IL-7 reference standard (NIBSC code: 90/530).Synonyms: IL7 | IL-7 | IL-7interleukin-7 | interleukin 7 | Lymphopoietin-1 | PBGF
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Recombinant Human LR3 IGF-I/IGF-1 GMP ProteinSpecies: Human Accession #: P05019.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured in a serum-free cell proliferation assay using MCF 7 human breast cancer cells. The ED50 for this effect is 0.3-1.5 ng/mL. IGFBP-3 does not inhibit its activity.Synonyms: IBP1 | IGF1 | IGF-1 | IGF1A | IGFI | IGF-I | IGF-IA | IGF-IB | insulin-like growth factor 1 (somatomedin C) | insulin...
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Recombinant Human KGF/FGF-7 GMP ProteinSpecies: Human Accession #: P21781.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using 4MBr 5 rhesus monkey epithelial cells.The ED50 for this effect is 6-60 ng/mL. The specific activity of recombinant human KGF/FGF-7 is >8.16 x 10^5 units/mg, which is calibrated against the human KGF/FGF-7 WHO Standard (NIBSC code: 03/150).Synonyms: FGF7 | FGF-7 | fibroblast growth factor 7HBGF-7 | HBGF7 | HBGF-7 | Heparin-binding growth factor 7 | keratinocyte gro...
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Recombinant Human IL-21 GMP ProteinSpecies: Human Accession #: Q9HBE4Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using B9 mouse hybridoma cells. The ED50 for this effect is 5.00-50.0 ng/mL. The specific activity of recombinant human IL-21 is >1.00 x 10^6 units/mg, which is calibrated against an internal reference standard for human IL-21.Synonyms: Interleukin 21 | CVID11 | IL21 | IL-21 | interleukin-21 | interleukin-21 isoform | Za11
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Recombinant Human IL-15 GMP ProteinSpecies: Human Accession #: P40933Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.300-2.60 ng/mL. The specific activity of recombinant human IL-15 is >2.00 x 10^8 units/mg, which is calibrated against the human IL-15 reference standard (NIBSC code: 95/554).Synonyms: Interleukin 15 | IL15 | IL-15 | MGC9721 | interleukin-15
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Recombinant Human IL-2 GMP ProteinSpecies: Human Accession #: P60568Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.0300-0.250 ng/mL. The specific activity of recombinant human IL-2 is >5.00 x 10^6 IU/mg, which is calibrated against the human IL-2 WHO International Standard (NIBSC code: 86/500).Synonyms: Interleukin 2 | Aldesleukin | IL2 | IL-2 | lymphokine | interleukin-2 | involved in regulation of T-cell clonal expan...
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Recombinant Human VEGF 165 GMP ProteinSpecies: Human Accession #: NP_001165097.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 1.50-12.0 ng/mL. The specific activity of recombinant human VEGF165 is > 8.0 x 10^5 units/mg, which is calibrated against the human VEGF165 WHO standard (NIBSC code: 02/286).Synonyms: MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VE...
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Recombinant Human TNF-alpha GMP ProteinSpecies: Human Accession #: P01375.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25-100 pg/mL. The specific activity of recombinant human TNF-α GMP is >4.3 x 10^7 IU/mg, which is calibrated against the human TNF-α WHO International Standard (NIBSC code: 12/154).Synonyms: APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
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Recombinant Human Thrombopoietin GMP ProteinSpecies: Human Accession #: NP_000451.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).Synonyms: Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating fac...
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Recombinant Human Betacellulin GMP ProteinSpecies: Human Accession #: P35070Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.100-1.50 ng/mL.Synonyms: Betacellulin | BTC | probetacellulin
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Recombinant Human Sonic Hedgehog/Shh (C24II) GMP ProteinSpecies: Human Accession #: NP_000184.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.1-0.4 µg/mL.Synonyms: HHG1 | HHG-1 | HLP3 | HPE3 | MCOPCB5 | MCOPCB5sonic hedgehog (Drosophila) homolog | Shh | ShhNC | SMMCI | SMMCIsonic ...
