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PharmPure™ GMP Portfolio
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Recombinant Human BMP-4 GMP ProteinSpecies: Human Accession #: P12644Expression system: E. coli Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Alkaline phosphatase production by ATDC-5 cells. ED50 approximately 95 ng/mL.Synonyms: Bone Morphogenetic Protein 4 | BMP2B | BMP-2B | BMP2B1 | MCOPS6 | BMP4 | BMP-4 | Bone morphogenetic protein 2B | DVR4...
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Recombinant Human Wnt-3a GMP ProteinSpecies: Human Accession #: NP_149122.1Expression system: HEK293 Protein Tag: C-hFc Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to induce Topflash reporterBioactivity in CHO-K1 cells. The ED50 for this effect is ＜30ng/ml.Synonyms: MGC119418 | MGC119419 | MGC119420 | protein Wnt-3a | wingless-type MMTV integration site family, member 3A | Wnt3a | ...
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Recombinant Human VEGF 165 GMP ProteinSpecies: Human Accession #: NP_001165097.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 1.50-12.0 ng/mL. The specific activity of recombinant human VEGF165 is > 8.0 x 10^5 units/mg, which is calibrated against the human VEGF165 WHO standard (NIBSC code: 02/286).Synonyms: MVCD1 | VAS | vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VE...
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Recombinant Human TNF-alpha GMP ProteinSpecies: Human Accession #: P01375.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25-100 pg/mL. The specific activity of recombinant human TNF-α GMP is >4.3 x 10^7 IU/mg, which is calibrated against the human TNF-α WHO International Standard (NIBSC code: 12/154).Synonyms: APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
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Recombinant Human Noggin GMP ProteinSpecies: Human Accession #: Q13253.1Expression system: HEK293 Protein Tag: C-hFc Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4Synonyms: NOG | Noggin | SYM1 | symphalangism 1 (proximal) | synostoses (multiple) syndrome 1 | SYNS1 | SYNS1A
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Recombinant Human Thrombopoietin GMP ProteinSpecies: Human Accession #: NP_000451.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).Synonyms: Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating fac...
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Recombinant Human TGF-beta 1 GMP ProteinSpecies: Human Accession #: P01137.2Expression system: CHO Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/mL.The specific activity of recombinant human TGF-β1 GMP is >1.0 x 10^7 units/mg, which is calibrated against the human TGF‑β1 Standard (NIBSC code: 89/514).Synonyms: CED | LAP | DPD1 | latency-associated peptide | TGF beta | TGF beta1 | TGFB | TGFB1 | TGF-beta 1 protein | TGFbeta 1 ...
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Recombinant Human Sonic Hedgehog/Shh (C24II) GMP ProteinSpecies: Human Accession #: NP_000184.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.1-0.4 µg/mL.Synonyms: HHG1 | HHG-1 | HLP3 | HPE3 | MCOPCB5 | MCOPCB5sonic hedgehog (Drosophila) homolog | Shh | ShhNC | SMMCI | SMMCIsonic ...
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Recombinant Human SCF GMP ProteinSpecies: Human Accession #: P21583.1Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 1.00-8.00 ng/mL. The specific activity of recombinant human SCF is >1.0 x 10^6 units/mg, which is calibrated against the human SCF reference standardSynonyms: c-kit Ligand | DCUA | DFNA69 | DKFZp686F2250 | familial progressive hyperpigmentation 2 | FPH2 | FPHH | KIT ligand | ...
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Recombinant Human PDGF-BB GMP ProteinSpecies: Human Accession #: P01127Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 1.5-6 ng/mL. The specific activity of recombinant human PDGF-BB is >7.5 x 10^5 IU/mg, which is calibrated against the human PDGF-BB WHO International Standard (NIBSC code: 94/728).Synonyms: c-sis | IBGC5 | PDGF2 | PDGF-2 | PDGFB | Platelet-derived growth factor subunit B | SIS | SSV | PDGFBB | PDGF-BB
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Recombinant Human IL-10 GMP ProteinSpecies: Human Accession #: P22301Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cell proliferation assay using MC/9‑2 mouse mast cells. The ED50 for this effect is 0.0750-0.750 ng/mL. The specific activity of recombinant human IL-10 is >2.50 x 10^6 units/mg, which is calibrated against the human IL-10 WHO Reference Reagent (NIBSC code: 93/722).Synonyms: Interleukin 10 | CSIF | MGC126450 | Cytokine synthesis inhibitory factor | GVHDS | IL10 | IL-10 | IL10A | MGC126451 |...
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Recombinant Human Apo-Transferrin ProteinSpecies: Human Accession #: P02787Expression system: CHO Protein Tag: No tag Endotoxin Concentration: <10 EU/mgBioactivity: 1、Measured in a serum-free cell proliferation assay using MDCK canine kidney epithelial cells. The ED50 for this effect is ≤5 μg/mL. 2、Measured in a cell proliferation assay using K562 human chronic myelogenous leukemia erythroleukemic cells. The ED50 for this effect is typically 39.45 ng/mL.Synonyms: Serotransferrin | Transferrin | Beta-1 metal-binding globulin | Siderophilin | TF | TFQTL1 | PRO1557 | PRO2086 | HEL-...
