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PDPH(3-(2-pyridyldithio)propionyl hydrazide) , CAS No.P638964

  • Molecular Weight:  229.32
In stock
Item Number
P638964
Grouped product items
SKU Size
Availability
Price Qty
P638964-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$542.90

PDPH

Basic Description

Storage Temp Store at 2-8°C,Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Product introduction:

PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Features of PDPH :

Reactive groups:pyridyldisulfide andhydrazide
Reactive toward: sulfhydryl groups and carbonyl (aldehyde) groups
• Short (9.2A), sulfhydryl-to-aldehyde crosslinker with disulfide bond spacer arm (cleavable)
• Pyridyldithiol group results in attachment to sulfhydryls via disulfide bond, which can be cleaved with DTT, TCEP or other reducing agents
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Reactive Moiety:Hydrazide,Pyridyldisulfide

Crosslinker Type:Heterobifunctional

Form:Powder:

Spacer:Short(<10 Å),Cleavable:By Thiols

Labeling Method:Chemical Labeling

Spacer Arm Length:9.2 Å

Product Properties

Reactivity Carbohydrate-Sulfhydryl

Names and Identifiers

Molecular Weight 229.32

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility DMF,DMSO

Solution Calculators

Reviews

Customer Reviews

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