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P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt - ≥95%, high purity , CAS No.102783-36-8

    Grade & Purity:
  • ≥95%
  • Cas Number:  102783-36-8
  • Molecular Weight:  836.39 (free acid basis)
  • PubChem CID: 59709
In stock
Item Number
P335868
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P335868-10mg
10mg
Available within 8-12 weeks(?)
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$319.90

a derivative of Diadenosine polyphosphate, which is stored in secretory granules of thrombocytes

Basic Description

Synonyms A(5′)p4(5′)A, Diadenosine tetraphosphate ammonium salt
Specifications & Purity ≥95%
Storage Temp Store at -20°C
Shipped In
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Product Description

A derivative of Diadenosine polyphosphate, which is stored in secretory granules of thrombocytes, chromaffin, and neuronal cells. Has been shown to function as a pancreatic cell secondary messenger, phospholipase D stimulator, change intracellular calcium levels, nitric oxide release inductor, 5′-nucleotidase activator and adenosine kinase activity inhibitor in vitro.

Purpose

P1,P4-Di(adenosine-5′) tetraphosphate ammonium salt has been used as a substrate for nudix hydrolyse. It has also been used as a ATP analog and nudix substrate for cleavage factor II Im25 subunit.

Names and Identifiers

IUPAC Name [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate;azane
INCHI InChI=1S/C20H28N10O19P4.4H3N/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(45-19)1-43-50(35,36)47-52(39,40)49-53(41,42)48-51(37,38)44-2-8-12(32)14(34)20(46-8)30-6-28-10-16(22)24-4-26-18(10)30;;;;/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H2,21,23,25)(H2,22,24,26);4*1H3/t7-,8-,11-,12-,13-,14-,19-,20-;;;;/m1..../s1
InChIKey COBCSHRAXKIEQE-LKZCCGPLSA-N
Smiles N.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)[C@@H](O)[C@H]3O
Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N.N.N.N.N
WGK Germany 3
RTECS AU7411600
PubChem CID 59709
Molecular Weight 836.39 (free acid basis)

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Soluble in water: 50 mg/mL
Melt Point(°C) 123-125° C

Solution Calculators

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