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Osocimab (anti-Factor XI) - Primary antibody, specific to F11, >95%, high purity, Human IgG1, Antibody of coagulation factor XI, Antibody of coagulation factor XI

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Rabbit
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175621
Grouped product items
SKU Size
Availability
Price Qty
Ab175621-100μg
100μg
10
$59.90
Ab175621-1mg
1mg
4
$259.90
Ab175621-5mg
5mg
1
$749.90
Ab175621-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Osocimab (anti-Factor XI) - Primary antibody, specific to F11, >95%, high purity, Human IgG1, Antibody of coagulation factor XI
Synonyms coagulation factor XI antibody | Coagulation factor XIa light chain antibody | F11 antibody | FA11_HUMAN antibody | FXI antibody | MGC141891 antibody | Plasma thromboplastin antecedent antibody | Platelet coagulation factor XI antibody | PTA antibody | Co
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity F11
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type NEGATIVE ALLOSTERIC MODULATOR
Mechanism of action Antibody of coagulation factor XI
Product Description

Osocimab (anti-Factor XI), an anti-FXIa antibody (Ki=2.4 nM; EC50=0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab (anti-Factor XI) inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab (anti-Factor XI) exhibits anticoagulant effects.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.0 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 186.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2056878-75-0

Associated Targets(Human)

F11 Tchem Coagulation factor XI (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Osocimab (anti-Factor XI) (Ab175621) - SEC
The purity of Osocimab (anti-Factor XI) (Ab175621) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303699 Certificate of Analysis Mar 26, 2024 Ab175621
ZJ24F0303698 Certificate of Analysis Mar 26, 2024 Ab175621
ZJ24F0303697 Certificate of Analysis Mar 26, 2024 Ab175621

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