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Navicixizumab (anti-DLL4) - Primary antibody, specific to DLL4, >95%, high purity, Human IgG2SA

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG2SA
  • Conjugation: Unconjugated
In stock
Item Number
Ab176598
Grouped product items
SKU Size
Availability
 Price Qty
Ab176598-100μg
100μg
10
$129.90
Ab176598-1mg
1mg
4
$649.90
Ab176598-5mg
5mg
1
$2,029.90
Ab176598-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,249.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: DLL4
Accession#:Q9NR61 (4) DLL4 (4) Gene ID:54567 (4)

Basic Description

Product Name Navicixizumab (anti-DLL4) - Primary antibody, specific to DLL4, >95%, high purity, Human IgG2SA
Synonyms AOS6 antibody | Delta 4 antibody | delta 4 precursor antibody | Delta ligand 4 antibody | delta ligand 4 precursor antibody | Delta like 4 antibody | Delta like 4 homolog antibody | Delta like 4 protein antibody | Delta like canonical Notch ligand 4 antib
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity DLL4
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Navicixizumab (anti-DLL4) is a bispecific anti-VEGF and anti-DLL4 inhibitory antibody. Navicixizumab (anti-DLL4) can combine with Paclitaxel (HY-B0015) for cancer research. Navicixizumab (anti-DLL4) can be used in the research of ovarian, primary peritoneal, or fallopian tube cancer.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG2SA
Light Chain Type kappa
SDS-PAGE 146.17 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1638338-43-8

Associated Targets(Human)

DLL4 Tbio Delta-like protein 4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Navicixizumab (anti-DLL4) (Ab176598) - Flow Cytometry
Flow Cytometry analysis of HUVEC cells labelling DLL4 (red) with Navicixizumab (anti-DLL4) (Ab176598). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Navicixizumab (anti-DLL4) (Ab176598) - SEC
The purity of Navicixizumab (anti-DLL4) (Ab176598) is more than 95% verified by HPLC.

Navicixizumab (anti-DLL4) (Ab176598) - ELISA
Immobilized human-DLL4-his a at 2.0 μg/mL can bind Navicixizumab (anti-DLL4) (Ab176598) with the EC₅₀ of 36.01 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404416 Certificate of Analysis Apr 11, 2024 Ab176598
ZJ24F0404415 Certificate of Analysis Apr 11, 2024 Ab176598
ZJ24F0404414 Certificate of Analysis Apr 11, 2024 Ab176598

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