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Narnatumab (anti-RON) - Primary antibody, specific to MST1R, >95%, high purity, Human IgG1, INHIBITOR of Macrophage-stimulating protein receptor inhibitor, INHIBITOR of Macrophage-stimulating protein receptor inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176214
Grouped product items
SKU Size
Availability
Price Qty
Ab176214-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
Ab176214-1mg
1mg
5
$649.90
Ab176214-5mg
5mg
1
$1,629.90
Ab176214-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,609.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Narnatumab (anti-RON) - Primary antibody, specific to MST1R, >95%, high purity, Human IgG1, INHIBITOR of Macrophage-stimulating protein receptor inhibitor
Synonyms c met related tyrosine kinase antibody | CD136 antibody | CD136 antigen antibody | CDw136 antibody | Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody | Macrophage stimulating 1 receptor antibody | Macrophage stimulating protein r
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MST1R
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Macrophage-stimulating protein receptor inhibitor
Product Description

Narnatumab (anti-RON) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab (anti-RON) can be used for the research of cancer.(注:Kd中的d为下标)
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.0 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 183.5 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1188275-92-4

Associated Targets(Human)

MST1R Tchem Macrophage-stimulating protein receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Narnatumab (anti-RON) (Ab176214) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling RON (red) with Narnatumab (anti-RON) (Ab176214). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101852 Certificate of Analysis Nov 29, 2023 Ab176214
ZJ23F1101851 Certificate of Analysis Nov 29, 2023 Ab176214

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