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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176214-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$129.90
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Ab176214-1mg
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1mg |
5
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$649.90
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Ab176214-5mg
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5mg |
1
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$1,629.90
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Ab176214-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,609.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Narnatumab (anti-RON) - Primary antibody, specific to MST1R, >95%, high purity, Human IgG1, INHIBITOR of Macrophage-stimulating protein receptor inhibitor |
|---|---|
| Synonyms | c met related tyrosine kinase antibody | CD136 antibody | CD136 antigen antibody | CDw136 antibody | Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody | Macrophage stimulating 1 receptor antibody | Macrophage stimulating protein r |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | MST1R |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Macrophage-stimulating protein receptor inhibitor |
| Product Description |
Narnatumab (anti-RON) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab (anti-RON) can be used for the research of cancer.(注:Kd中的d为下标) |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.0 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 183.5 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1188275-92-4 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Narnatumab (anti-RON) (Ab176214) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling RON (red) with Narnatumab (anti-RON) (Ab176214). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 29, 2023 | Ab176214 | |
| Certificate of Analysis | Nov 29, 2023 | Ab176214 |
Starting at $109.90
Starting at $109.90