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N2-Methyl-L-arginine - 96%, high purity , CAS No.2480-28-6

COA COA
    Grade & Purity:
  • ≥96%
  • Cas Number:  2480-28-6
  • Molecular Weight:  188.23
  • PubChem CID: 73046
In stock
Item Number
N287385
Grouped product items
SKU Size
Availability
 Price Qty
N287385-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$155.90
N287385-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
N287385-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$918.90
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Lysosomal system c L-arginine uptake inhibitor

Basic Description

Synonyms N~2~-methyl-L-arginine | (2S)-5-guanidino-2-(methylamino)pentanoic acid | (2S)-5-(diaminomethylideneamino)-2-(methylamino)pentanoic acid | 88RBJ4ZE9R | (S)-5-Guanidino-2-methylamino-pentanoic acid | J-015678 | UNII-88RBJ4ZE9R | (2S)-5-{[amino(imino)methyl
Specifications & Purity ≥96%
Biochemical and Physiological Mechanisms Selective L-arginine uptake inhibitor (Ki= 500μM). Inhibits uptake of arginine by the lysosomal system c in human fibroblastin vitro.
Storage Temp Room temperature
Shipped In Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct Parent L-alpha-amino acids
Alternative Parents Fatty acids and conjugates  Guanidines  Amino acids  Propargyl-type 1,3-dipolar organic compounds  Monocarboxylic acids and derivatives  Dialkylamines  Carboxylic acids  Carboximidamides  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic acyclic compounds
Substituents L-alpha-amino acid - Fatty acid - Guanidine - Amino acid - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Secondary amine - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors Not available

Associated Targets(Human)

NOS1 Tchem Nitric oxide synthase, brain (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
NOS3 Tchem Nitric oxide synthase, endothelial (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NOS3 Tchem Nitric-oxide synthase, endothelial (1452 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NOS1 Tchem Nitric oxide sythases; iNOS & nNOS (685 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAW264.7 (28094 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (2S)-5-(diaminomethylideneamino)-2-(methylamino)pentanoic acid
INCHI InChI=1S/C7H16N4O2/c1-10-5(6(12)13)3-2-4-11-7(8)9/h5,10H,2-4H2,1H3,(H,12,13)(H4,8,9,11)/t5-/m0/s1
InChIKey NTWVQPHTOUKMDI-YFKPBYRVSA-N
Smiles CNC(CCCN=C(N)N)C(=O)O
Isomeric SMILES CN[C@@H](CCCN=C(N)N)C(=O)O
Molecular Weight 188.23
Reaxy-Rn 27313981
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27313981&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Solvent:water, Max Conc. mg/mL: 18.82, Max Conc. mM: 100
Molecular Weight 188.230 g/mol
XLogP3 -3.700
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 6
Exact Mass 188.127 Da
Monoisotopic Mass 188.127 Da
Topological Polar Surface Area 114.000 Ų
Heavy Atom Count 13
Formal Charge 0
Complexity 189.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 1
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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