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| SKU | Size | Availability |
Price | Qty |
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N423174-1ml
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1ml |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$74.90
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Polyamine used for precipitation of DNA from low salt aqueous buffers.
| Synonyms | Spermine tetrahydrochloride | 306-67-2 | N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride | Gerontine tetrahydrochloride | Neuridine tetrahydrochloride | Musculamine tetrahydrochloride | N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride | |
|---|---|
| Specifications & Purity | 10mM in Water |
| Biochemical and Physiological Mechanisms | Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic nitrogen compounds |
| Class | Organonitrogen compounds |
| Subclass | Amines |
| Intermediate Tree Nodes | Secondary amines |
| Direct Parent | Dialkylamines |
| Alternative Parents | Organopnictogen compounds Monoalkylamines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Primary amine - Primary aliphatic amine - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen. |
| External Descriptors | Not available |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| IUPAC Name | N,N'-bis(3-aminopropyl)butane-1,4-diamine;tetrahydrochloride |
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| INCHI | InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H |
| InChIKey | XLDKUDAXZWHPFH-UHFFFAOYSA-N |
| Smiles | C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl |
| Isomeric SMILES | C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl |
| WGK Germany | 3 |
| RTECS | EJ7230000 |
| Alternate CAS | 1255099-40-1 |
| PubChem CID | 9384 |
| Molecular Weight | 348.18 |
| Reaxy-Rn | 3911771 |
| Sensitivity | Hygroscopic |
|---|---|
| Melt Point(°C) | 315°C |
| Molecular Weight | 348.200 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 8 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 11 |
| Exact Mass | 348.12 Da |
| Monoisotopic Mass | 346.122 Da |
| Topological Polar Surface Area | 76.100 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 86.100 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 5 |