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N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride - 10mM in Water, high purity , CAS No.306-67-2

    Grade & Purity:
  • 10mM in Water
  • Cas Number:  306-67-2
  • Molecular Weight:  348.18
  • PubChem CID: 9384
In stock
Item Number
N423174
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N423174-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$74.90

Polyamine used for precipitation of DNA from low salt aqueous buffers.

Basic Description

Synonyms Spermine tetrahydrochloride | 306-67-2 | N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride | Gerontine tetrahydrochloride | Neuridine tetrahydrochloride | Musculamine tetrahydrochloride | N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride |
Specifications & Purity 10mM in Water
Biochemical and Physiological Mechanisms Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
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Product Description

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic nitrogen compounds
Class Organonitrogen compounds
Subclass Amines
Intermediate Tree Nodes Secondary amines
Direct Parent Dialkylamines
Alternative Parents Organopnictogen compounds  Monoalkylamines  Hydrochlorides  Hydrocarbon derivatives  
Molecular Framework Aliphatic acyclic compounds
Substituents Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Primary amine - Primary aliphatic amine - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
External Descriptors Not available

Associated Targets(Human)

PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
nfo Endonuclease 4 (425 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name N,N'-bis(3-aminopropyl)butane-1,4-diamine;tetrahydrochloride
INCHI InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChIKey XLDKUDAXZWHPFH-UHFFFAOYSA-N
Smiles C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl
Isomeric SMILES C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl
WGK Germany 3
RTECS EJ7230000
Alternate CAS 1255099-40-1
PubChem CID 9384
Molecular Weight 348.18
Reaxy-Rn 3911771

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity Hygroscopic
Melt Point(°C) 315°C
Molecular Weight 348.200 g/mol
XLogP3
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 11
Exact Mass 348.12 Da
Monoisotopic Mass 346.122 Da
Topological Polar Surface Area 76.100 Ų
Heavy Atom Count 18
Formal Charge 0
Complexity 86.100
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 5

Solution Calculators

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