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N-decanoyl-L-Homoserine lactone - ≥96%, high purity , CAS No.177315-87-6

1 Citations

COA

Grade & Purity:

≥96%

Cas Number: 177315-87-6
Molecular Weight: 255.35
PubChem CID: 10131281
PubChem SID: 504765274

In stock

Item Number

N347574

Grouped product items
SKU	Size	Availability	Price
N347574-5mg	5mg	1	$37.90
N347574-10mg	10mg	2	$64.90
N347574-25mg	25mg	2	$149.90
N347574-50mg	50mg	2	$249.90
N347574-100mg	100mg	1	$399.90

a small signaling molecule involved in quorum sensing

View related series

Anti-infection (2803) Bacterial (3013) Glucose Metabolism (1943) Metabolic Enzyme/Protease (4860)

Basic Description

Synonyms	BDBM50351509 \| Decanoyl-L-homoserine lactone \| SCHEMBL3140223 \| J-011268 \| MFCD11113140 \| AS-67956 \| N-[(3S)-2-oxooxolan-3-yl]decanamide \| Q27461120 \| N-Decanoyl-L-homoserine lactone, >=96% (HPLC) \| N-Decanoyl-L-Homoserine lactone \| HY-136409 \| (S)-N-(2-o
Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	N-DECANOYL L-l-proserine lactone is a member of N-ACYL-PROSERINE lactone family. N-ACYLHOMOSERINE lactone (Ahl) regulates gene expression in Gram-negative such as ESCHERICHIA coli (Echerichia) and Salmonella, and is involved in quorum sensing and cell-to-
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	N-decanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include regulation of virulence and exoproteases.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 N-acyl-alpha amino acids and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent	N-acyl-alpha amino acids and derivatives
Alternative Parents	Alpha amino acid esters Acyl-L-homoserine lactones N-acyl amines Gamma butyrolactones Oxolanes Secondary carboxylic acid amides Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Alpha-amino acid ester - N-acyl-alpha amino acid or derivatives - Acyl-homoserine lactone - Acyl-l-homoserine lactone - Fatty amide - Gamma butyrolactone - N-acyl-amine - Fatty acyl - Oxolane - Secondary carboxylic acid amide - Lactone - Carboxylic acid ester - Carboxamide group - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Oxacycle - Organooxygen compound - Organonitrogen compound - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

luxR Transcriptional activator protein luxR (400 Activities)

Discover Target: luxR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

traR Transcriptional activator protein traR (147 Activities)

Discover Target: traR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lasR Transcriptional activator protein lasR (432 Activities)

Discover Target: lasR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504765274
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504765274
IUPAC Name	N-[(3S)-2-oxooxolan-3-yl]decanamide
INCHI	InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
InChIKey	TZWZKDULKILUPV-LBPRGKRZSA-N
Smiles	CCCCCCCCCC(=O)NC1CCOC1=O
Isomeric SMILES	CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Molecular Weight	255.35
Reaxy-Rn	1644700
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1644700&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot Number	Certificate Type	Date	Item
E2209056	Certificate of Analysis	Feb 07, 2025	N347574
E2209050	Certificate of Analysis	Feb 07, 2025	N347574
J2417545	Certificate of Analysis	Oct 09, 2024	N347574
J2417549	Certificate of Analysis	Oct 09, 2024	N347574
J2417550	Certificate of Analysis	Oct 09, 2024	N347574
J2417551	Certificate of Analysis	Oct 09, 2024	N347574
J2417552	Certificate of Analysis	Oct 09, 2024	N347574
J2417555	Certificate of Analysis	Oct 09, 2024	N347574
J2417581	Certificate of Analysis	Oct 09, 2024	N347574
A2410026	Certificate of Analysis	Feb 24, 2022	N347574
E2209058	Certificate of Analysis	Feb 24, 2022	N347574
E2209051	Certificate of Analysis	Feb 24, 2022	N347574
J2317049	Certificate of Analysis	Feb 24, 2022	N347574
D2324570	Certificate of Analysis	Feb 24, 2022	N347574
E2410072	Certificate of Analysis	Feb 24, 2022	N347574

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Chemical and Physical Properties

Solubility	Soluble in ethanol (~5 mg/ml), DMSO (~20 mg/ml), DMF (~30 mg/ml), water (10 mg/ml at 25° C), and 1: 4 DMF: PBS (pH 7.2) (~0.2 mg/ml).
Refractive Index	n20D1.48 (Predicted)
Boil Point(°C)	~466.1° C at 760 mmHg (Predicted)
Melt Point(°C)	166.93° C (Predicted)
Molecular Weight	255.350 g/mol
XLogP3	3.700
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	9
Exact Mass	255.183 Da
Monoisotopic Mass	255.183 Da
Topological Polar Surface Area	55.400 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	266.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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