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| SKU | Size | Availability |
Price | Qty |
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A275214-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$166.90
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Sphingolipid ceramide derivative
| Synonyms | ACETYLPHYTOSPHINGOSINE | CCG-208163 | Enamine_005139 | 1-(pyridin-2-yl)acetone | C2 Phytoceramide (t18:0/2:0) | Acetamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]- | UNII-RZ4494XR10 | ACETYLPHYTOSPHINGOSINE [INCI] | N-02:0 Phytosphingosin |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Sphingolipid ceramide derivative. Induces caspase-dependent apoptosis. Anticancer agent. Potential NF-κB and JAK/STAT signaling inhibitor. Active in vitro and potentially in vivo . |
| Storage Temp | Store at -20°C,Argon charged,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Sphingolipids |
| Subclass | Ceramides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phytoceramides |
| Alternative Parents | Acetamides Secondary carboxylic acid amides Secondary alcohols Polyols Primary alcohols Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | N-acyl-4-hydroxysphinganine - Acetamide - Carboxamide group - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Polyol - Primary alcohol - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as phytoceramides. These are n-acylated 4-hydroxysphinganine. |
| External Descriptors | Not available |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| IUPAC Name | N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]acetamide |
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| INCHI | InChI=1S/C20H41NO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19(24)20(25)18(16-22)21-17(2)23/h18-20,22,24-25H,3-16H2,1-2H3,(H,21,23)/t18-,19+,20-/m0/s1 |
| InChIKey | SZUJJDLBXJCDNT-ZCNNSNEGSA-N |
| Smiles | CCCCCCCCCCCCCCC(C(C(CO)NC(=O)C)O)O |
| Isomeric SMILES | CCCCCCCCCCCCCC[C@H]([C@H]([C@H](CO)NC(=O)C)O)O |
| Molecular Weight | 359.55 |
| Reaxy-Rn | 2418854 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2418854&ln= |
| Solubility | Soluble in ethanol and in DMSO (with warming) |
|---|---|
| Molecular Weight | 359.500 g/mol |
| XLogP3 | 4.900 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 17 |
| Exact Mass | 359.304 Da |
| Monoisotopic Mass | 359.304 Da |
| Topological Polar Surface Area | 89.800 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 312.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |