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N-Acetylphytosphingosine (NAPS) - ≥98%, high purity , CAS No.21830-28-4

    Grade & Purity:
  • ≥98%
In stock
Item Number
A275214
Grouped product items
SKU Size
Availability
Price Qty
A275214-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$166.90

Sphingolipid ceramide derivative

View related series
Apoptosis (4276)

Basic Description

Synonyms ACETYLPHYTOSPHINGOSINE | CCG-208163 | Enamine_005139 | 1-(pyridin-2-yl)acetone | C2 Phytoceramide (t18:0/2:0) | Acetamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]- | UNII-RZ4494XR10 | ACETYLPHYTOSPHINGOSINE [INCI] | N-02:0 Phytosphingosin
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Sphingolipid ceramide derivative. Induces caspase-dependent apoptosis. Anticancer agent. Potential NF-κB and JAK/STAT signaling inhibitor. Active in vitro and potentially in vivo .
Storage Temp Store at -20°C,Argon charged,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class Sphingolipids
Subclass Ceramides
Intermediate Tree Nodes Not available
Direct Parent Phytoceramides
Alternative Parents Acetamides  Secondary carboxylic acid amides  Secondary alcohols  Polyols  Primary alcohols  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic acyclic compounds
Substituents N-acyl-4-hydroxysphinganine - Acetamide - Carboxamide group - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Polyol - Primary alcohol - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as phytoceramides. These are n-acylated 4-hydroxysphinganine.
External Descriptors Not available

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

BCHE Cholinesterase (8742 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]acetamide
INCHI InChI=1S/C20H41NO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19(24)20(25)18(16-22)21-17(2)23/h18-20,22,24-25H,3-16H2,1-2H3,(H,21,23)/t18-,19+,20-/m0/s1
InChIKey SZUJJDLBXJCDNT-ZCNNSNEGSA-N
Smiles CCCCCCCCCCCCCCC(C(C(CO)NC(=O)C)O)O
Isomeric SMILES CCCCCCCCCCCCCC[C@H]([C@H]([C@H](CO)NC(=O)C)O)O
Molecular Weight 359.55
Reaxy-Rn 2418854
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2418854&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Soluble in ethanol and in DMSO (with warming)
Molecular Weight 359.500 g/mol
XLogP3 4.900
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 17
Exact Mass 359.304 Da
Monoisotopic Mass 359.304 Da
Topological Polar Surface Area 89.800 Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 312.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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