Mocravimod hydrochloride (KRP-203), an immunosuppressant, is a potent and orally active S1PR1 (sphingosine 1-phosphate receptor type 1) agonist.
Storage Temp
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Mocravimod hydrochloride (KRP-203), an immunosuppressant, is a potent and orally active S1PR1 (sphingosine 1-phosphate receptor type 1) agonist
In Vivo
Mocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R ?/? Mice . ?\nMocravimod hydrochloride (KRP-203) (orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection in mHC-disparate rat heart allografts. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Inbred male DA (MHC haplotype: RT1 a ) ratsDosage: 0.1 and 1 mg/kg Administration: Orally; daily; for 100 days Result: Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts.
