This is a demo store. No orders will be fulfilled.

Milatuzumab (anti-CD74) - Primary antibody, specific to CD74, >95%, high purity, Human IgG1, Antibody of CD74, Antibody of CD74

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175598
Grouped product items
SKU Size
Availability
Price Qty
Ab175598-100μg
100μg
10
$69.90
Ab175598-1mg
1mg
4
$339.90
Ab175598-5mg
5mg
1
$869.90
Ab175598-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,379.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Milatuzumab (anti-CD74) - Primary antibody, specific to CD74, >95%, high purity, Human IgG1, Antibody of CD74
Synonyms CD 74 antibody | CD74 antibody | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody | CD74 antigen antibody | CD74 molecule antibody | CD74 molecule, major histocompatibility complex, class II in
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD74
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of CD74
Product Description

Milatuzumab (anti-CD74) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab (anti-CD74) causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumab (anti-CD74) also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.7 kDa (Light Chain) & 50.7 kDa (Heavy Chain), under reducing conditions; 199.9 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 899796-83-9

Associated Targets(Human)

CD74 Tchem HLA class II histocompatibility antigen gamma chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD74 Tchem HLA-DR antigens-associated invariant chain (25 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Milatuzumab (anti-CD74) (Ab175598) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD74 (red) with Milatuzumab (anti-CD74) (Ab175598). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Milatuzumab (anti-CD74) (Ab175598) - SEC
The purity of Milatuzumab (anti-CD74) (Ab175598) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0403992 Certificate of Analysis Apr 01, 2024 Ab175598
ZJ24F0403991 Certificate of Analysis Apr 01, 2024 Ab175598
ZJ24F0403990 Certificate of Analysis Apr 01, 2024 Ab175598

Alternative Products

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.