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CD74 Mouse mAb - Primary antibody, specific to CD74, Mouse IgG1

    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: LN2
  • Conjugation: Unconjugated
In stock
Item Number
Ab095284
Grouped product items
SKU Size
Availability
Price Qty
Ab095284-10μg
10μg
10
$26.90
Ab095284-50μg
50μg
4
$69.90
Ab095284-100μg
100μg
2
$109.90
Ab095284-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90

mAb (LN2); Mouse anti Human CD74 Antibody; Flow; Unconjugated

Basic Description

Product Name CD74 Mouse mAb - Primary antibody, specific to CD74, Mouse IgG1
Synonyms CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated) | CD74 antigen | CD74 molecule, major histocompatibility complex, class II invariant chain | CD74 | CLIP | DHLAG | DHLAGgamma chain of class II antigens |
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, See COA
Host species Mouse
Specificity CD74
Immunogen SU-DHL-4 cells.
Positive Control Flow: Human peripheral blood lymphocytes.
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD74 Antibody, Monoclonal (LN2), could be used for Flow and so on.

Application

Flow: 1.0 μg/100w cells

Protein Function

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

CD74 Tchem HLA class II histocompatibility antigen gamma chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD74 Tchem HLA-DR antigens-associated invariant chain (25 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD74 (red) with CD74 Mouse mAb (Ab095284) at 0.5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD74 (red) with CD74 Mouse mAb (Ab095284) conjugated with biotin at 2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

CD74 Mouse mAb (Ab095284) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD74 with CD74 Mouse mAb (Ab095284) conjugated with biotin (right panel) at 2 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Application

Application Dilution info
Flow Cytometry

1μg/100w cells

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404675 Certificate of Analysis Apr 19, 2024 Ab095284
ZJ24F0404674 Certificate of Analysis Apr 19, 2024 Ab095284
ZJ24F0404673 Certificate of Analysis Apr 19, 2024 Ab095284

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