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Metipranolol hydrochloride - 99%, high purity , Beta-1 adrenergic receptor antagonist, CAS No.36592-77-5, Beta-1 adrenergic receptor antagonist

COA

Grade & Purity:

≥99%

Cas Number: 36592-77-5
Molecular Weight: 345.86
PubChem CID: 656682

In stock

Item Number

M651911

Grouped product items
SKU	Size	Availability	Price
M651911-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$209.90
M651911-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$335.90
M651911-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$670.90
M651911-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,187.90

View related series

Adrenergic Receptor (261) Class A GPCR (4138) GPCR/G Protein (3172) Neuronal Signaling (3320)

Basic Description

Synonyms	METIPRANOLOL HYDROCHLORIDE \| MS-25314 \| PHENOL, 4-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)-2,3,6-TRIMETHYL-, 1-ACETATE, HYDROCHLORIDE (1:1) \| FBW237ALKD \| (+/-)-1-(4-HYDROXY-2,3,5-TRIMETHYLPHENOXY)-3-(ISOPROPYLAMINO)-2-PROPANOL 4-ACETATE HYDROCHLORIDE
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Action Type	ANTAGONIST
Mechanism of action	Beta-1 adrenergic receptor antagonist
Product Description	Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent. In Vitro Metipranolol is used systemically for the treatment of arterial hypertension and topically for the management of glaucoma. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:β adrenergic receptor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Phenol esters

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Phenol esters
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Phenol esters
Alternative Parents	Phenoxy compounds Phenol ethers Alkyl aryl ethers Secondary alcohols Carboxylic acid esters Amino acids and derivatives 1,2-aminoalcohols Monocarboxylic acids and derivatives Dialkylamines Organopnictogen compounds Organic oxides Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Phenol ester - Phenoxy compound - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - 1,2-aminoalcohol - Amino acid or derivatives - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Secondary amine - Secondary aliphatic amine - Ether - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrochloride - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organopnictogen compound - Amine - Organic oxygen compound - Alcohol - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenol esters. These are aromatic compounds containing a benzene ring substituted by a hydroxyl group and an ester group.
External Descriptors	organic chloride salt
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-2,3,6-trimethylphenyl] acetate;hydrochloride
INCHI	InChI=1S/C17H27NO4.ClH/c1-10(2)18-8-15(20)9-21-16-7-11(3)17(22-14(6)19)13(5)12(16)4;/h7,10,15,18,20H,8-9H2,1-6H3;1H
InChIKey	BLWNYSZZZWQCKO-UHFFFAOYSA-N
Smiles	CC1=CC(=C(C(=C1OC(=O)C)C)C)OCC(CNC(C)C)O.Cl
Isomeric SMILES	CC1=CC(=C(C(=C1OC(=O)C)C)C)OCC(CNC(C)C)O.Cl
PubChem CID	656682
Molecular Weight	345.86

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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8 results found

Lot Number	Certificate Type	Date	Item
K2404523	Certificate of Analysis	Aug 15, 2024	M651911
K2404524	Certificate of Analysis	Aug 15, 2024	M651911
K2404525	Certificate of Analysis	Aug 15, 2024	M651911
K2404526	Certificate of Analysis	Aug 15, 2024	M651911
K2404527	Certificate of Analysis	Aug 15, 2024	M651911
K2404528	Certificate of Analysis	Aug 15, 2024	M651911
K2404529	Certificate of Analysis	Aug 15, 2024	M651911
K2404530	Certificate of Analysis	Aug 15, 2024	M651911

Chemical and Physical Properties

Solubility	H2O : ≥ 100 mg/mL (289.13 mM) DMSO : 100 mg/mL (289.13 mM; Need ultrasonic)
Sensitivity	Moisture sensitive
Molecular Weight	345.900 g/mol
XLogP3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	345.171 Da
Monoisotopic Mass	345.171 Da
Topological Polar Surface Area	67.800 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	348.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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